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Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Medicinal prophylaxis of restenosis after lower limb arterial reconstructive surgery

[Original research] [Surgery]
Roman Kalinin; Igor Suchkov; Alexandr Pshennikov; Alexandr Slepnyov;

The article represents data on efficacy of different drugs in prevention of restenosis after lower limb arterial reconstructive surgery. The efficacy of L-arginine, perindopril, losartan and nebivolol was evaluated in comparison with the control group. The incidence of neointimal hyperplasia and bypass thrombosis was found to be lower in the cases of endothelium directed therapy.

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References:
1. Belov Yu.V., Stepanenko A.B. Povtornye rekonstruktivnye operatsii na aorte i magistralnykh arteriyakh. M.: «Mosk. inform. agentstvo»; 2009. 176 р.
2. Shvalb P.G. i dr. Angiologiya i sosudistaya khirurgiya. – Angiology and Vascular Surgery. 2007;13(4):144-146.
3. Grigoryev N.B., Granik V.G. Oksid azota (NO). Novy put k poisku lekarstv. M.: «Vuzovskaya kniga»; 2004. 360 р.
4. Kirichuk V.F., Glybochko P.V., Ponomareva A.I. Disfunktsiya endoteliya. Saratov: «Izd-vo Saratovskogo med. un-ta»; 2008. 129 р.
5. Pokrovsky A.V. Klinicheskaya angiologiya. M.: «Meditsina»; 2004.
6. Natsionalnye rekomendatsii po vedeniyu patsiyentov s sosudistoy arterialnoy patologiyey. Chast 1. Perifericheskiye arterii. M.; 2010. 78 р.
7. Shvalb P.G., Kalinin R.E. Khirurgiya. Zhurnal imeni N.I. Pirogova (Surgery). 2009;1:53-55.
8. Kalinowski L. et al. Hypertension. 2002;40(4):521-527.
9. Bachmann S., Mundel P. Am J Kidney Dis. 1994;24:112-129.
10. Hirooka Y. et al. J Am Coll Cardiol. 1994;24:948-955.
11. Hornig B., Kohler C., Drexler H. Circulation. 1997;95:1115-1118.

Keywords: nitric oxide, neointimal hyperplasia, restenosis, endotheliotropic therapy


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy