Site search
Correspondence address
310 Mira Street, Stavropol, Russia, 355017
Tel
+7 865 2352511, +7 865 2353229.
E-mail
medvestnik@stgmu.ru
The journal is included into The list of leading scientific periodicals.
The journal is included into VINITI database and is registered in Electronic scientific library.
The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.
[Original research] [Surgery]
Oksana Vladimirova; Peter Lavreshin; Sergey Minaev; Alexandr Muravyev; Vitaly Olegovich Tsvetkov; Vakhtang Gobejishvili; Igor Babich; Anton Vladislavovich Terehin; Yulia Lukash;
Treating patients with burns and massive wounds while the complications only start to develop, including pathological scarring (PS), is the most urgent task that purulent and reconstructive surgery currently faces. The study involved following up forty-two patients (age range: 21–59 years) suffering from traumatic injuries and burns wounds. Patients were broken into equal groups, namely, a study group and a control group. All this done to evaluate the efficiency of wound healing auto-stimulation through using a cold plasma flow and introducing platelet-enriched autoplasma. The outcomes the study produced point to the fact that the impact of the proposed complex provides an improvement of the healing process by an average of 4.5±0.3 days, also reducing the risk of the patient developing PS. The reason is a faster, rapid, and homogenous recovery entailed by stimulated epithelization
References:
1. Callaghan D. J. Review on the treatment of scars. Plastic and Aesthetic Research. 2020;7:66. https://doi.org/10.20517/2347-9264.2020.166
2. Vladimirova O. V., Grigorova A. N., Gobedzhishvili V. V., Minaev S. V., Vladimirov V. I., Burkovskaya O. G. A met hod of autodermoplasty with a split skin flap for resto ring the skin in case of burns. RF patent for an invention № 2753136 dated 11.08.2021. https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&locale=en_EP&CC=RU&NR=2753136C1&KC=C1
3. Urakova Е. V. Non-invasive methods of prevention and treatment of facial pathological scars. Practical Medicine. 2017;8(109):133-137.
4. Bochkova Т. V., Gantsev S. H. Platelet-rich autoplasma in various areas of medicine. Bashkortostan Medical Journal.2019;14(5):61-67.
5. Andreeva V. V., Kuzmina E. N. Modern View on classification of cicatricial skin deformations. Medical Technologies. Assessment and Choice. 2018;4(34):83-86. https://doi.org/10.31556/2219-0678.2018.34.4.083-086
6. Chernyakov А. V. Prevention and treatment of pathological scars in surgical practice. Russian Medical Journal.2017;25(28):2063-2068.
7. Golyanovsky O. V., Ivankova I. N. Сomparative prognostic value of ultrasound and mri diagnostic methods for anomalously invasive placenta. women’s health. 2018;8(134):65-65.
8. Baranovsky Y. G., Ilchenko F. N., Shapovalova E. Y. Prevention treatment for keloid and hypertrophic scars. surgery of injuries and critical conditions. Pirogov Forum digest. 2017;4:291-292.
9. Vladimirova O. V., Lavreshin P. M., Vladimirov V. I., Grigorova A. N., Gobedzhishvili V. V. [et al.] Platelet-rich Disclosures: The authors declare no conflict of interest. autoplasma use at early stages of wound healing to prevent pathological scar development. Medical News of North Caucasus. 2021;16(2):203-205. https://doi.org/10.14300/mnnc.2021.16047
10. Li J., Hu W.P., Zhong G. Clinical therapeutic effects of platelet-rich plasma in patients with burn wound healing: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021;100(31):e26404. https://doi.org/10.1097/MD.0000000000026404
11. Minaev S. V., Grigorova A. N., Timofeev S. I., Obedin A. N., Gerasimenko I. N. [et al.] Development of the adhesive process in the abdominal cavity using plastic devices in laparoscopic surgery. Medical News of North Caucasus. 2022;17(2):206-208. https://doi.org/10.14300/mnnc.2022.17051
12. Knowles A., Glass D. A. 2nd. Keloids and Hypertrophic Scars. Dermatol. Clin. 2023;41(3):509-517. https://doi.org/10.1016/j.det.2023.02.010
13. Nabai L., Pourghadiri A., Ghahary A. Hypertrophic Scarring: Current Knowledge of Predisposing Factors, Cellular and Molecular Mechanisms. J. Burn. Care Res. 2020 Jan. 30;41(1):48-56. https://doi.org/10.1093/jbcr/irz158
14. Minaev S. V., Vladimirova O. V., Kirgizov I. V., Akselrov M. A.,Razin M. P. [et al.] Multicenter study of the effectiveness of antiscar therapy in patients at different age periods. Pirogov Russian Journal of surgery. = Khirurgiya. Zurnal im. N. I. Pirogova. 2020;(9):51-59. https://doi.org/10.17116/hirurgia202009159
15. Eremenko E., Ding J., Kwan P., Tredget E. E. The Biology of Extracellular Matrix Proteins in Hypertrophic Scarring. Adv. wound Care (New Rochelle). 2022 May;11(5):234-254. https://doi.org/10.1089/wound.2020.1257
Keywords: platelet-rich autoplasma, epithelization, autodermaplasty, pathological scarring