Site search
Correspondence address
310 Mira Street, Stavropol, Russia, 355017
Tel
+7 865 2352511, +7 865 2353229.
E-mail
medvestnik@stgmu.ru
The journal is included into The list of leading scientific periodicals.
The journal is included into VINITI database and is registered in Electronic scientific library.
The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.
[Experimental medicine]
Sergey Sirak; Evgeny Shchetinin; Roman Romanenko;
The results of an X-ray assessment of the dynamics of bone regeneration of postoperative defects in an experiment on rats using a stress-inducing device to form non-physiological occlusion of the jaws are presented. More effective and complete restoration of the alveolar ridge after tooth extraction was shown in animals treated intraperitoneally with ethylmethylhydroxypyridine succinate under chronic stress conditions. X-ray analysis of the bone regeneration confirmed the stimulation of bone healing by the drug in terms of 30 and 60 days in the form of filling the defect with trabecular bone, which, in terms of quantitative and qualitative composition, can provide the function of a scaffold for newly formed vessels and nerves.
References:
1. Abdullah Alqahtani N., Chandramoorthy H. C., Shaik S., Syed J., Chowdhary R. [et al.] Bone Marrow Mesenchymal Stromal Cells (BMMSCs) Augment Osteointegration of Dental Implants in Type 1 Diabetic Rabbits: An X-Ray Micro-Computed Tomographic Evaluation. Medicina. 2020;56(4):148. https://doi.org/10.3390/medicina56040148
2. Hu B., Meng Z. D., Zhang Y. Q., Ye L. Y., Wang C. J. [et al.] A scaffolds fabricated by SPS technology promote the repair of segmental bone defects. Tissue Cell. 2020;66:101386. https://doi.org/10.1016/j.tice.2020.101386
3. Fiorellini J. P., Sourvanos D., Sarimento H., Karimbux N., Luan K. W. Periodontal and Implant Radiology. Dent. Clin. North. Am. 2021;65(3):447-473. https://doi.org/10.1016/j.cden.2021.02.003
4. Christiaens V., De Bruyn H., Thevissen E., Koole S., Dierens M. [et al.] Assessment of periodontal bone level revisited: a controlled study on the diagnostic accuracy of clinical evaluation methods and intra-oral radiography. Clin. Oral Investig. 2018;22(1):425-431. https://doi.org/10.1007/s00784-017-2129-8
5. Baturin V. A., Fisher V. V., Sergeev S. A., Yatsuk I. V. The influence of premedication containing mexidol on cortisol level and number of ß-adrenergic receptors in the postoperative period. Medical News of North Caucasus. 2016;11(4):590-591. https://doi.org/10.14300/mnnc.2016.11144
6. Sirak S. V., Petrosyan G. G., Shchetinin E. V., Romanenko R. G., Tarabrina A. G. [et al.] Stress-induced disorders of the metabolic activity of periodontal tissue in experimental animals and possibility of its correction. Medical News of North Caucasus. 2018;13(2):395-399. https://doi.org/10.14300/mnnc.2018.13060
7. Ashizawa Y., Sahara N. Quantitative evaluation of newly formed bone in the alveolar wall surrounding the root during the initial stage of experimental tooth movement in the rat. Arch. Oral Biol. 1998;43(6):473-84. https://doi.org/10.1016/s0003-9969(98)00017-x
8. Kim T. S., Obst C., Zehaczek S., Geenen C. Detection of bone loss with different X-ray techniques in periodontal patients. J. Periodontol. 2008;79(7):1141-1149. https://doi.org/10.1902/jop.2008.070578
9. Górski B., Jalowski S., Górska R., Zaremba M. Treatment of intrabony defects with modified perforated membranes in aggressive periodontitis: subtraction radiography outcomes, prognostic variables, and patient morbidity. Clin. Oral Investig. 2019;23(7):3005-3020. https://doi.org/10.1007/s00784-018-2712-7
Keywords: radiography, experiment, osseointegration, chronic stress