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Improvement of H. Pylori eradication therapy efficiency in patients with ischemic heart disease

[Original research]
Natalia Kireeva; Andrey Svistunov; Mikhail Osadchuk;

In 110 patients with chronic atrophic gastritis associated with Helicobacter pylori against the background of hypercholesterolemia and exertional angina of functional class I–II study of the efficiency of eradication therapy has been conducted. Our results suggest a significant role for the level of blood cholesterol in the formation of antibiotic resistance during H. pylori eradication. Normalization of cholesterol levels increased the effectiveness of treatment, which makes it reasonable to use statins during eradication of H. pylori in chronic atrophic gastritis.

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Keywords: ischemic heart disease, H. pylori eradication, cholesterol, statins


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Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy