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ISSN 2073-8137
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Experience in the implementation of pharmacogenetic testing in clinical practice at the administration of statin group drugs . Analysis of long -term therapy results.

[Clinical Pharmacology]
Nikolai Rumyantsev; Vladimir Kukes; Dmitry Grapov;

The prevalence of carriage of various genotypes of the SLCO1B1 gene and the possible effect of the genotypes of the SLCO1B1 gene on the effectiveness and safety of statin therapy at the hospital stage were assessed, as well as an analysis of the long-term results of the therapy. The feasibility of using pharmacogenetic testing in patients when prescribing drugs of the statin group and the main problems in their use in clinical practice are discussed.

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Keywords: statins, personalized medicine, pharmacogenetics


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