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Bioresorbable membranes based on polyvinyl alcohol and fullerene

[Experimental medicine]
Gennady Grebnev; Aleksandr Ivanov; Andrey Vasilievich Kabankov; Musa Magomedovich Garunov; Vasily Rumakin; Irina Borodulina;

In this study, resorbable membranes based on polyvinyl alcohols with varying degrees of hydrolysis and fullerene (C60) were implanted under the femoral muscles of 73 outbred white mice with the aim of targeted bone tissue regeneration. The results of morphological studies showed that the final resorption of the membranes was achieved within 90 days. In the control group that was implanted with membranes based on polyvinyl alcohols without C 60, the membranes became encapsulated and did not undergo bioresorption within 90 days.

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Keywords: tissue regeneration, resorbable membrane, fullerene, morphological study


Founders:
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Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy