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Heart remodeling and quality of life in patients with chronic kidney disease on renal replacement therapy

[Original research]
Svetlana Urazlina; Tatiana Zhdanov; Tatiana Zueva; Elena Viktorovna Kuznetcova;

The correlation between structural and hemodynamic parameters of the heart and Quality of life (QOL) parameters have been studied in chronic kidney disease (CKD) patients on hemodialysis (HD), continuous ambulatory peritoneal dialysis (CAPD) and kidney transplant recipients (KTR). Patients were divided into three groups according to the type of RRT. CKD stage 3 patients were in the control group. The significant correlation has been founded between the values of the myocardial mass index (LVMI), end-diastolic size (LVEDS), end-diastolic volume (LVEDV), end-systolic size (LVESS), end-systolic volume (LVESV), ejection fraction (LVEF) of the left heart ventricle and QOL among patients on RRT with minimal structural and functional changes in the heart. A negative correlation has been founded between LVMI, LVEDS, LVEDV and physical health component (PF). A decrease in LVEF, as well as an increase in LVESS and LVESV, was associated with the deterioration in both indicators of physical (PF, RP) and psychological health (SF).

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Keywords: quality of life, renal replacement therapy, structural changes in the left heart v entricle


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