Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
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ISSN 2073-8137

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Influence of metabolic syndrome on the clinical picture of osteoarthrosis

[Original research] [Internal diseases]
Lyudmila Vasilyeva; Dmitry Lakhin;

The effect of metabolic syndrome on the clinical picture and laboratory parameters of osteoarthritis was studied in 164 patients, divided depending on its presence or absence on the main and control groups. The number and location of affected joints, the severity of the pain syndrome, the values of ESR, C-reactive protein and tumor necrosis factor-α
were assessed. Patients with osteoarthritis and metabolic syndrome experienced more frequent joint damage, as well as more pronounced pain and inflammation intensity.


1. Kratnov A. E., Lopatnikova E. N., Kratnov A. A. Sakharnyj diabet. – Diabetes Mellitus. 2002;15(2):13-16. doi: 10.14341/2072-0351-5512
2. Nasonov E. L., Aleksandrova E. N., Novikov A. A. Vestnik Rossijskoj akademii meditsinskikh nauk. – Annals of the Russian academy of medical sciences. 2015;70(2):169- 182. doi:10.15690/vramn.v70i2.1310
3. Solov’eva I. V., Strebkova E. A., Alekseeva L. I., Mkrtumyan A. M. Ozhirenie i metabolizm. – Obesity and Metabolism. 2014;11(4):41-47. doi: 10.14341/omet2014441-47
4. Baranova A. V. Russian Journal of Genetics. 2008;44(10):1338-1355. doi: 10.1134/s1022795408100050
5. Caporali R., Cimmino M. A., Sarzi-Puttini P., Scarpa R., Parazzini F., Zaninelli A., Ciocci A., Montecucco C. Sem. Arthritis Rheum. 2005;35(1):31-37. doi: 10.1016/j. semarthrit.2005.02.004
6. Daskalopoulou S. S., Mikhailidis D. P., Elisaf M. Angiology. 2004;55(6):589-612. doi: 10.1177/00033197040550i601
7. Ford E. S. Atherosclerosis. 2004;173(2):309-314. doi: 10.1016/j.atherosclerosis.2003.12.022
8. Jacobsson L. T., Turesson C., Hanson R. L., Pillemer S., Sievers M. L., Pettitt D. J., Bennett P. H., Knowler W. C. Arthritis Rheum. 2001;44:1170-1176. doi: 10.1002/1529-0131(200105)44:5 3.0.co;2-t
9. Kadam U. T., Jordan K., Croft P. R. Ann. Rheum. Dis. 2004; 63(4): 408-414. doi:10.1136/ard.2003.007526
10. Orellana C., Navarro N., Vázquez I., Moreno M., Galisteo C., Gratacós J., Larrosa M. Osteoarthritis and Cartilage. 2011;19(1):142. doi: 10.1016/S1063- 4584(11)60333-6
11. Wenham C. Y. J., Grainger A. J., Conaghan P. G. Osteoarthritis and Cartilage. 2014;22(10): 692-1702. doi:10.1016/j.joca.2014.06.005

Keywords: metabolic syndrome, osteoarthritis, comorbidity

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy