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Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Experimental prevention of amyloidosis in syrian hamsters

[Experimental medicine]
Zalina Kisieva; Vadim Brin;

The aim of the study was to investigate the prophylactic effect of Mildronat and Atsizol on morphological and functional renal parameters in animals undergone the native sheep plasma injection.
In the experiment, the simultaneous injection of Acyzol and Mildronat since the early period of the native sheep plasma injection contributes to the reduction of the amyloid nephropathy manifestations. We detected less severely impaired renal filtration capacity, tubular water reabsorption, sodium and potassium and calcium excretion, reduction of proteinuria. Histological study of the kidneys, heart, liver and spleen tissue revealed a decreased amyloid accumulation in the stromal-vascular structures.

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Keywords: amyloid nephropathy, potassium and calcium excretion, renal filtration capacity, tubular water reabsorption


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