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ISSN 2073-8137
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Pathomorphological changes of dental pulp in experimental osteoporosis

[Experimental medicine]
Sergey Sirak; Evgeny Shchetinin; Alla Sirak; Ivan Koshel; Magomet Aybazov; Marina Vafiadi; Anatolii Adamchik;

The study focused on pathomorphological changes taking place in the tooth pulp in sheep in case of experimental osteoporosis. The pulp was extracted after cracking the teeth. The sections were stained with hematoxylin and eosin by Masson, and impregnated with silver by Foot and Bielschowsky-Gros. There were severe vascular disturbances detected (vasodilation, stasis, perivascular edema with cell infiltration, hemorrhages), which resulted in vacuolization of odontoblasts, pulp reticular dystrophy, disintegration of argyrophilic and nerve structures. Such disturbances came along with proliferation of cell elements in the connective tissue and in nerve elements with denticle development.

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Keywords: osteoporosis, pulp, experiment, odontoblasts


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