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https://doi.org/10.14300/mnnc.2016.11038

Do non-clostridial anaerobic bacteria cause of acute pyelonephritis in ureter obstruction?

[Experimental medicine]
Dmitry Pasechnik; Michail Kogan; Evgeniya Mitusova; Yulia Naboka; Z. Gazayev; Halid Ibishov; I. Gudima; Saro Bejanyan;

The problem of etiology and pathogenesis of acute obstructive pyelonephritis remains an outstanding issue in modern urology. The infectious nature of acute destructive renal processes presently remains disputed. Etiologic agents of pyelonephritis may be both gram-negative and gram-positive opportunistic bacteria, the majority of which is part of normal human microflora. Presently, several publications delegated that role to non-clostridial anaerobic microorganisms, found in tissue substrates in as much as 99.0 % of cases. But their contribution to the etiology and pathogenesis of urinary tract infections is presently not sufficiently investigated. The experiment studies the morphologic specifics of acute obstructive pyelonephritis caused by various taxa of non-clostridia anaerobic bacteria. The data obtained changed the existing views on the detection and influence of said group of microorganisms upon the course of acute pyelonephritis in ureter obstruction.

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References:
1. Naboka Y. L., Kogan M. I., Gudima I. A., Chernickaja M. L., Ibishev Kh. S. Role of non-clostridial anaerobes in the development of infectious and inflammatory diseases of the urinary and reproductive systems. Urology. 2013;4:16-18.
2. Kogan M. I., Naboka Y. L., Gudima I. A., Gazaev Z. I., Ibishev Kh. S. et al. New view on etiological structure of the acute obstructive pyelonephritis. Contemporary problems of science and formation. 2012;4. www.science-education.ru.
3. Apostolopoulou C., Konstantoulaki S., Androulakakis P., Vatopoulou T., Varkarakis M. Isolation of anaerobic organisms from kidney in serious renal infections. Urology. 1982;20(5):479-481.
4. Brook I. Urinary tract infection caused by anaerobic bacteria in children. Urology. 1980;16(6):596-598.
5. DuPrey K. M., McCrea L., Rabinowitch B. L., Azad K. N. Pyelonephritis and Bacteremia from Lactobacillus delbrueckii. Case Rep. Infect. Dis. 2012;10:1155-1158.
6. Giamarellos-Bourboulis E., Adamis T., Laoutaris G., Sabracos L., Koussoulas V. Immunomodulatory clarithromycin treatment of experimental sepsis and acute pyelonephritis caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 2004;48(1):93-99.
7. Lattenist L., Teske G., Claessen N., Florquin S., Conway E. M. The lectin like domain of trombomodulin is involved in the defence against pyelonephritis. Trombosis research. 2015;136:1325-1331.
8. Katsaris M. P., Adamis T., Pistiki A., Carrer D.-P., Galani I. Immunomodulatory Intervention with Interferon-g in Escherichia coli Pyelonephritis. Journal of Urology. 2014;192(2):600-606.
9. Pasechnik D. G., Kogan M. I., Naboka J. L., Ibishev Kh. S., Gazaev Z. I. The experimental model of obstructive acute pyelonephritis induced non-clostridial infection. Virchows Arch. 2011;2:290–291.
10. Plotnikov E. Y.. Pulkova N. V., Pevzner I. B., Zorova L. D., Silachev D. N. Inflammatory pre-conditioning of mesenchymal multipotent stromal cells improves their immunomodulatory potency in acute pyelonephritis in rats. Cytotherapy. 2013;15(6):679-689.
11. Sapico F. L., Wideman P. A., Finegold S. M. Aerobic and anaerobic flora in bladder urine of patients with indwelling urethral catheters. Urology. 1976;7(4):382-384.
12. Schulte T. L. Bacteroides and anaerobic streptococci in infection of the urinary tract. Proc. Mayo Clin. 1939;14:536.
13. Siddiqui H., Nederbragt A. J., Lagesen K., Jeansson S. L., Jakobsen K. S. Assesing diversity of the female urine microbiota by high throughput sequencing of 16S RNA amplicons. BMC Microbiol. 2011;11:244-251.

Keywords: acute obstructive pyelonephritis, non-clostridial anaerobic bacteria, urinary tract infection, morphological changes