logo
Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
rus
русский
eng
english

Site search



Correspondence address
310 Mira Street, Stavropol, Russia, 355017

Tel
+7 865 2352511, +7 865 2353229.

E-mail
medvestnik@stgmu.ru

Pathophysiological mechanisms behind experimental odontogenic maxillitis

[Experimental medicine]
Vladimir Koshel; Evgeny Shchetinin; Sergey Sirak;

This item offers a view on the outcomes of an experimental study involving an animal model, while the study was aimed at clarifying the clinical and morphological changes taking place in the maxillary tissues in case of odontogenic inflammation. The experiment was carried out on 30 guinea-pigs, where each of these had its right-side maxillary sinus as experimental, while the left side was observed as control. The simulated odontogenic infection focus in maxillary paradontium tissues was shown to cause purulent inflammation in the paranasal sinuses on the two sides, both in the intact and in the sensibilized animals, while in the sensibilized ones the pathology in the mucosa resulted in cyst-like formation development.

Download

References:
1. Bravo Cordero G., Minzer Ferrer S., Fernández L. Odontogenic sinusitis, oro-antral fistula and surgical repair by Bichat’s fat pad: Literature review. Acta Otorrinolaringologica Espanola. 2016;67(2):107-113. doi: 10.1016/j.otorri.2015.03.001
2. Brook I. Sinusitis of odontogenic origin. Otolaryngology – Head and Neck Surgery, 2006;135(3):349-355. doi: 10.1016/j.otohns.2005.10.059
3. Grigoryanz L. A., Sirak S. V., Zekeryaev R. S. Pokazaniya effektivnost ispolzovaniya razlichnich hirurgicheskih vmeshatelstv pri lechenii bolnich s odontogennim gaimoritom. Stomatologia – Dentistry. 2007;86(3):42-46.
4. Grimm W. D., Dannan A., Giesenhagen B. Тranslational research: palatal-derived ecto-mesenchymal stem cells from human palate: a new hope for alveolar bone and cranio-facial bone reconstruction. International Journal of Stem Cells. 2014;7(1):23-29.
5. Grimm W.-D., Ploger M., Schau I. Сomplex, three-dimensional reconstruction of critical size defects following delayed implant placement using stem cell-containing subepithelial connective tissue graft and allogenic human bone blocks for horizontal alveolar bone augmentation: a case report as proof of clinical study principles. Medical news of North Сaucasus. 2014;9(2):131-133. doi: 10.14300/mnnc.2014.09037
6. Grimm W. D., Plöger M., Schau I. Рrefabricated 3d allogenic bone block in conjunction with stem cell-containing subepithelial connective tissue graft for horizontal alveolar bone augmentation: a case report as proof of clinical study principles. Medical news of North Сaucasus. 2014;9(2):175-178. doi: 10.14300/mnnc.2014.09050
7. Longhini A. B., Branstetter B. F., Ferguson B. J. Otolaryngologists’ perceptions of odontogenic maxillary sinusitis. Laryngoscope. 2012; 122 (9): 1910-1914. doi: 10.1002/lary.23427
8. Mikhalchenko D. V., Poroshin A. V., Mikhalchenko V. F. Influence of transcranial electrostimulation on the osseointegration of dental implant in the experiment. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014;5(5):705-711.
9. Sirak S. V., Sirak A. G. Morfofunkcionalnie izmeneniya v pulpe zubov eksperimentalnich zhivotnich pri lechenii glubokogo kariesa i ostrogo ochagovogo pulpita. Sovremennye problemy nauki i obrazovanija – Modern problems of science and education. 2013;2:44.
10. Sirak S. V., Sletov A. A., Loktionova M. V. Diagnostika, lechenie I profilaktika verhnechelustnogo sinusita, voznikayuschego posle endodonticheskich vmeshatelstv. Parodontologiya – Parodontology. 2008;3:14-18.
11. Sirak S. V., Ibragimov I. M., Kodzokov B. A. Sposob subantralnoy augmentacii kosti dlya ustanovki dentalnoich implantatov pri atrofii alveolyarnogo otrostka verchney chelusti / Patent RUS 2469675, 09.11.2011.
12. Sirak S. V., Shchetinin E. V., Sletov A. A. Subantralnaya augmentaciya poristim titanom v eksperimente i klinike. Stomatologiya – Dentistry. 2016;95(1):55-58.
13. Sirak S. V., Avanesyan R. A., Akkalaev A. B. Мicrobiocenosis of oral cavity in patients with dental implants and over-dentures. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014;5(5):698-704.
14. Sirak S. V., Arutyunov A. V., Shchetinin E. V. Сlinical and morphological substantiation of treatment of odontogenic cysts of the maxilla. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014;5(5):682-690.

Keywords: maxillary sinus, mucosa, odontogenic sinusitis


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy