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Pathophysiological mechanisms behind experimental odontogenic maxillitis

[Experimental medicine]
Vladimir Koshel; Evgeny Shchetinin; Sergey Sirak;

This item offers a view on the outcomes of an experimental study involving an animal model, while the study was aimed at clarifying the clinical and morphological changes taking place in the maxillary tissues in case of odontogenic inflammation. The experiment was carried out on 30 guinea-pigs, where each of these had its right-side maxillary sinus as experimental, while the left side was observed as control. The simulated odontogenic infection focus in maxillary paradontium tissues was shown to cause purulent inflammation in the paranasal sinuses on the two sides, both in the intact and in the sensibilized animals, while in the sensibilized ones the pathology in the mucosa resulted in cyst-like formation development.

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Keywords: maxillary sinus, mucosa, odontogenic sinusitis


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