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https://doi.org/10.14300/mnnc.2015.10085

Vitamins concentration after bariatric surgery

[Surgery]
Natalya Bodunova; Igor Khatkov; Elena Sabelnikova; Acfold Parfenov; Rashid Askerkhanov; Elena Tkachenko; Galina Varvanina; Ilya Fyodorov; Sergey Mosin;

100 obese patients aged 19 to 61 years (78 women, 22 men) were investigated. Adjustable gastric banding (AGB) was performed in 20 patients, sleeve gastrectomy (SG) – in 40 patients and gastric bypass (GB) – in 40 patients. The control group consisted of 10 healthy subjects. The blood serum concentrations of vitamins B1, B2, B5, B6, B9, B12, C, D, niacin, biotin, and retinol-binding protein (RBP) were measured before and 1 year after surgery. There was a significant reduction of vitamins C, B6, B5, D and retinol-binding protein (RBP) before and after bariatric surgery as well. More than half of patients after SG also had reduction of niacin at baseline. A year after bariatric surgery (AGB, SG, and GB) the number of patients with the deficiency of these vitamins remained the same or increased. GB had no significant effect on the concentration of folic acid, vitamins B2, B12, B1 and Biotin. In 80 % of obese patients concentrations of vitamins C, B6 and D were reduced to various degrees. The number of patients with low concentrations of vitamins C, D, B6, B5, niacin, folic acid and RBP in the blood serum increased after bariatric surgery, while the number of patients having a lack of folic acid increases by more than 2 times. Bariatric surgery doesn’t have a significant impact on the metabolism of vitamins B1, B2, B12 and biotin.

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References:
1. Bodunova N. A, Sabelnikova E. A., Parfenov A. I. Terapevtichesky arkhiv. – Therapeutic Archives. – 2013;85(10):98-104.
2. Rebrov V. G., Gromova О. А. Vitamini, macro- i microelementi. 2008. P. 153-172.
3. Al-Shoha A., Quin S., Palniktar S. Endocr Pract. 2009;15(6):528-533.
4. Bhan A., Rao A. D., Rao D. S. Endocrinol. Metab. Clin. North Am. 2010;39(2):321-331.
5. Brolin R. E., Gorman J. H., Gorman R. C. J. Gastrointest Surg. 1998;2:436-442.
6. Fried M., Yumuk V., Oppert J.-M., Scopinaro N., Torres A. J., Weiner R., Yashkov Y., Frühbeck G. Obes Facts. 2013;6:449-468.
7. Gasteyger C., Suter M., Calmes J. M., Gaillard R. C., Giusti V. Obes Surg. 2006;16:243-250.
8. Gollobin C., Marcus W. Y. Obes Surg. 2002;12:309-311.
9. Halverson J. D. American Surgeon. 1986;52(11):594-598.
10. John S., Hoegeri C. J. Am. Osteopath. Assoc. 2009;109(11):601-604.
11. Kaidar-Person O., Rosenthal R. J. Minerva Chir. 2009;64(3):297-302.
12. Kramer L. D, Locke E. J. Clin. Gastroenterol. 1987;9:549-552.
13. Lakhani S. V., Shah H. N., Alexander K., Finelle F. C. Nutr. Res. 2008:28:293-298.
14. MacLean L. D., Rhode B. M., Shizgal H. M. Ann. Surg. 1983;198(3):347-355.
15. Munoz-Farjas E., Jerico I., Pascual-Millan L. F., Mauri J. A., Morales-Asin F. Rev. Neurol. 1996;24:456-458.
16. Rhode B. M., Arseneau P., Cooper B. A., Katz M., Gilfix B. M., MacLean L. D. Am. J. Clin. Nutr. 1996;63(1):103-109.
17. Seehra H., MacDermott N., Lascelles R. G., Taylor T. V. B. M. J. 1996;312:434.
18. Sola E., Morillas C., Garzon S. Obes Surg. 2003;13:661-662.

Keywords: bariatric surgery, malabsorption, vitamins, diagnostics