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EBSCO

https://doi.org/10.14300/mnnc.2023.18060

Overall survival of patients with liver cirrhosis

[Original research] [Internal diseases]
Vladislav Vladimirovich Petkau; Elena Nikolaevna Bessonova; Valery Vladimirovich Breder; Alisa Alekseevna Karimova;

The study of the life expectancy of patients with liver cirrhosis and the analysis of the causes of their mortality structure are still of scientific and practical interest. The study presents data of the 994 patients with liver cirrhosis overall survival and causes of mortality. Median of overall survival (OS) in Child – Pugh C class was 22.2 months, B class was 59.8 months, and A class was not achieved. The lowest indicators of OS were in B class of patients with liver cirrhosis of the alcohol etiology and non-alcoholic fatty liver disease, the patients with alcohol addiction had the worst prognosis (median of 13.9 months). Statistically significant differences in the occurrence of liver failure, which prevails in the structure of mortality among all observed patients, were confirmed.

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Keywords: liver cirrhosis, overall survival, causes of mortality, hepatocellular cancer, Child – Pugh