logo
Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
rus
русский
eng
english

Site search



Correspondence address
310 Mira Street, Stavropol, Russia, 355017

Tel
+7 8652 352524; +7 8652 353229.

Fax
+7 8652 352524.

E-mail
medvestnik@stgmu.ru

Influence of load on modeling and remodeling of bone tissue in experimental perimplantitis

[Experimental medicine]
Sergey Sirak; Maria Olegovna Didenko; Alla Sirak; Elizaveta Evgenievna Shchetinina; Ekaterina Sergeevna Sirak; Alina Vladimirovna Pogozheva; Gregory Petrosyan; Vadim Nikolaevich Lenev;

The article presents the results of a study of the features of osseointegration of dental implants in experimental perimplantitis, in which perimplant defects of the jaw healed in the control group under a blood clot, and were filled with a mixture of calcium hydroxyapatite and tricalcium phosphate modified with hyaluronic acid in the main group. The aim of the study was to assess the intensity of reparative bone regeneration in the perimplant zone in static and with chewing loads. As a result of the study, it was found that early functional loads on dental implants do not contribute to acceleration of the processes of modeling and remodeling of bone tissue in perimplantitis, and the use of osteoplastic material based on calcium sulfate modified with hyaluronic acid is comparable in effectiveness with reparative bone regeneration in the perimplant zone during natural healing of a wound under a blood clot, providing active autogenous neovasculogenesis due to hematopoietic stem cells in the early period (1–3 months).

Download

References:
1. Branemark P. I., Hansson B. O., Adell R. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scandinavian Journal of Plastic and Reconstructive Surgery. Supplementum. 1977;16:1-132.
2. Elani H. W., Starr J. R., Da Silva J. D., Gallucci G. O. Trends in Dental Implant Use in the U.S., 1999–2016, and Projections to 2026. Journal of Dental Research. 2018;97(13):1424-1430. https://doi.org/10.1177/0022034518792567
3. Kim J.-J., Lee J.-H., Kim J. C., Lee J.-B., Yeo I.-S. L. Biological Responses to the Transitional Area of Dental Implants: Material- and Structure-Dependent Responses of Peri-Implant Tissue to Abutments. Materials (Basel). 2020;13(1):72. https://doi.org/10.3390/ma13010072
4. Cortellini S., Favril C., De Nutte M., Teughels W., Quirynen M. Patient compliance as a risk factor for the outcome of implant treatment. Periodontology 2000. 2019;1(81):209-225. https://doi.org/10.1111/prd.12293
5. Messias A., Nicolau P., Guerra F. Titanium dental implants with different collar design and surface modifications: A systematic review on survival rates and marginal bone levels. Clinical Oral Implants Research. 2019;30(1):20-48. https://doi.org/10.1111/clr.13389
6. Francetti L., Cavalli N., Taschieri S., Corbella S. Ten years follow-up retrospective study on implant survival rates and prevalence of peri-implantitis in implant-supported full-arch rehabilitations. Clinical Oral Implants Research. 2019;3(30):252-260. https://doi.org/10.1111/clr.13411
7. French D., Grandin H. M., Ofec R. Retrospective cohort study of 4,591 dental implants: Analysis of risk indicators for bone loss and prevalence of peri-implant mucositis and peri-implantitis. Journal of Periodontology. 2019;90(7):691-700. https://doi.org/10.1002/JPER.18-0236
8. Kulakov A. A., Volozhin A. M., Tkachenko V. M., Doktorov A. A., Ibrahim Samir Salim. Usilenie osteointegracii dental’nogo implantata, napylennogo biokeramikoj, s pomoshh’ju gelja na osnove gialuronovoj kisloty i gidroksiapatita v jeksperimente. Stomatologija. – Dentistry. 2007;86(6):4-9. (In Russ.).
9. Garunov M. M., Sevbitov A. V., Dolgalev A. A., Sirak S. V., Solovyeva O. A. [et al.]. Clinical and radiographic assessment of osteointegration of dental implants after remodeling of the perimplant zone. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2019;14(4):699-700. (In Russ.). https://doi.org/10.14300/mnnc.2019.14174
10. Sirak S. V., Andreev A. A., Rubnikovich S. P., Sletov A. A., Kochkarova Z. M. [et al.]. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2020;15(1):107-111. (In Russ.). https://doi.org/10.14300/mnnc.2020.15025

Keywords: modeling, remodeling, bone tissue, jaw, experiment, perimplantitis


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy