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[Original research] [Internal diseases]
Alexandr Yagoda; Pavel Koroy; Guzel Gilyazova;
Plasma levels of E-selectin, L-selectin and P-selectin were studied in 101 patients with chronic viral liver diseases in relationship with hepatic histologic changes.
The levels of E-selectin, L-selectin and P-selectin in blood were increased in patients with chronic viral liver diseases with more high values of E-selectin and P-selectin in patients with liver cirrhosis. In chronic viral liver diseases concentration of E-selectin, L-selectin and P-selectin in blood increases with intensifying of the degree of inflammation and severity of hepatic fibrosis. The association of morphological changes in liver with selectins underlines their important role in occurrence and progressing of chronic viral liver diseases.
References:
1. Yagoda A.V., Koroy P.V. Eksperimentalnaya klinicheskaya gastroenterologiya. – Experimental Clinical Gastroenterology. 2006;5:73-76.
2. Abou-Saleh H., Theoret J.F., Yacoub D., Merhi Y. Thromb. Haemost. 2005;94:1230-1235.
3. Campbell J.S. et al. PNAS. 2005;102(9):3389-3394.
4. Iredale J.P. J Clin Invest. 2007;117:539-548.
5. Kawasuji A., Hasegawa M., Horikawa M. et al. J Leukoc Biol. 2006;79(4):696-705.
6. Klintman D., Li X., Thorlacius H. Clin Diagn Lab Immunol. 2004;11(1):56-62.
7. Laschke M.W., Dold S., Menger M.D. et al. Br J Pharmacol. 2008;153:148-156.
8. Laschke M., Menger M.D., Wang Y. et al. Am J Physiol Gastroenterol Hepatol Physiol. 2007;292:G1396-G1402.
9. Lv P., Luo H.S., Zhou X.P. et al. Arch Med Res. 2007;38(1):15-27.
10. Lv P., Luo H.S., Zhou X.P. et al. Pathol Res Pract. 2006;202(11):777-788.
11. March S, Garsia-Pagan J.C., Massaguer A. et al. Liver Int. 2005;25(5):1053-1060.
12. Massaguer A., Perez-Del-Pulgar S., Engel P. et al. J Leukoc Biol. 2002;72(2):262-270.
13. Montalto G., Giannitrapani L., Soresi M. et al. Inflammation. 2001;25(2):101-108.
14. Panasiuk A., ZakJ., Kasprzycka E. et al. World J Gastroenterol. 2005;11(18):2754-2758.
15. Panasiuk A., Prokopowicz D., Panasiuk B. World J Gastroenterol. 2004;10(24):3639-3642.
16. Paul S.C., Lv P., Xiao Y. et al. Pathobiology. 2006;73(2):82-92.
17. Pinzani M., Rombouts K., Colagrande S. J Hepatol. 2005;42:22-36.
18. Pitchford S.C., Momi S., Giannini S. et al. Blood. 2005;105:2074-2081.
19. Pockros P.J. J Clin Gastroenterol. 2006;40(6):461-463.
20. Sampietro T., Neglia D., Bionda A. et al. Am J Cardiol. 2005;96:1718-1720.
21. Tacke F., Schoffski P., Trautwein C. et al. Blood Coagul Fibrinolysis. 2003;14(4):319-325.
22. Vestweber D. Immunol Rev. 2007; 218:178-196.
23. Von Hundelshausen P., Weber C. Circ Res. 2007;100:27-40.
24. Wynn T.A., Hesse M., Sandler N.G. et al. Hepatology. 2004;39(3):676-687.
25. Yu Z., Otsuka H., Yamaguchi K. et al. Biochim Biophys Acta. 2011;1812(9):1069-1079.
Keywords: chronic viral hepatitis, liver cirrhosis, E-selectin, P-selectin, L-selectin