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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Selectins and histological changes in chronic viral liver diseases

[Original research] [Internal diseases]
Alexandr Yagoda; Pavel Koroy; Guzel Gilyazova;

Plasma levels of E-selectin, L-selectin and P-selectin were studied in 101 patients with chronic viral liver diseases in relationship with hepatic histologic changes.

The levels of E-selectin, L-selectin and P-selectin in blood were increased in patients with chronic viral liver diseases with more high values of E-selectin and P-selectin in patients with liver cirrhosis. In chronic viral liver diseases concentration of E-selectin, L-selectin and P-selectin in blood increases with intensifying of the degree of inflammation and severity of hepatic fibrosis. The association of morphological changes in liver with selectins underlines their important role in occurrence and progressing of chronic viral liver diseases.

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Keywords: chronic viral hepatitis, liver cirrhosis, E-selectin, P-selectin, L-selectin


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Pyatigorsk State Research Institute of Balneotherapeutics
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