logo
Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
rus
русский
eng
english

Site search



Correspondence address
310 Mira Street, Stavropol, Russia, 355017

Tel
+7 865 2352511, +7 865 2353229.

E-mail
medvestnik@stgmu.ru

Living organ donation: development trends

[Reviews]
Olga Petrovna Abaeva; Sergey Vladimirovich Romanov;

During the period of an intense discussion regarding a new Russian law regulating organ donation and transplantation, the authors of the following article have analyzed currently existing laws and literary sources from all over the world concerning this field, in order to discover the world tendencies of organ donation, regulations and procedures. The research has shown that the attitude towards risk-evaluation by a potential donor has changed drastically during the last quarter of a century. Besides, the countries that actively develop programs of organ transplantation have shifted from requiring a genetical connection between the donor and the recipient towards other factors describing their relations. In Russia, the law making process has demonstrated only slight hints of transitioning from genetical to relative-based donation, which is certainly falling behind international norms. This defines the necessity to provide active and profound work to propagate the humanity of organ donation.

Download

References:
1. Henderson M. L., Gross J. A. Living Organ Donation and Informed Consent in the United States: Strategies to Improve the Process. The Journal of Law, Medicine & Ethics. 2017;54(1):66-67. https://doi.org/l 0.1177/1073110517703101
2. Ghahramani N. Living Organ Donation; An Ethical Evolution or Evolution of Ethics? International Journal of organ transplantation medicine. 2010;1(2):57-62. PMID: 25013566
3. Nguyen T., Vazquez M., Toto R. Living kidney donation and hypertension risk. Lancet. 2007;369(9556):87-88. https://doi.org/l 0.1016/S0140-6736(07)60046-4
4. Lentine K. L., Patel A. Risks and Outcomes of Living Donation. Advances in chronic kidney disease. 2012;19(4):220-228. https://doi.org/10.1053/j.ackd.2011.09.005
5. Allen M., Abt P., Reese P. «What are the Harms of Refusing to Allow Living Kidney Donation»? An Expanded View of Risks and Benefits. American Journal of Transplantation. 2014;14(3):531-537. https://doi.org/10.l111/ajt.12599
6. Reese P. R., Boudville N., Garg A. X. Living kidney donation: outcomes, ethics, and uncertainty. The Lancet. 2015;385(9981):2003-2013. https://doi.org/l0.1016/SO140-6736( 14)62484-3
7. Gaston R. S., Kumar V., Matas A. J. Reassessing Medical Risk in Living Kidney Donors. Journal of the American Society of Nephrology. 2015;26(5):1017-1019. https://doi.org/10.1681/ASN.2014030227
8. Flanigan W. J., Burns R. O., Takacs F. J., Merrill J. P. Serial studies of glomerular filtration rate and renal plasma flow in kidney transplant donors, identical twins, and allograft recipients. American journal of surgery. 1968;116(5):788-794. https://doi.org/10.1016/0002-9610(68)90370-X
9. Fehrman-Ekholm I., Elinder C. G., Stenbeck M., Tyden G., Groth C. G. Kidney donors live longer. Transplantation. 1997;64(7):976-978. https://doi.org/10.1097/00007890-199710150-00007
10. Ibrahim H. N., Foley R., Tan L., Rogers T., Bailey R. F. [et al.]. Long-term consequences of kidney donation. The New England Journal of Medicine. 2009;360(5);459-469. https://doi.org/10.1056/NEJMoa0804883
11. Okamoto M., Akioka K., Nobori S., Ushigome H., Kozaki K. [et al.]. Short- and long-term donor outcomes after kidney donation: Analysis of 601 cases over a 35-year period at Japanese single center. Transplantation. 2009;87(3):419-423. https://doi.org/10.1097/TP.0b013e318192dc95.10.1097/TP.0b013e318192dc95
12. Kasiske B. L., Anderson-Haag T., Ibrahim H. N., Pesavento T. E., Weir M. R. [et al.]. A prospective controlled study of kidney donors: baseline and 6-month follow-up. American Journal of kidney diseases. 2013;62(3):577-586. https://doi.org/10.1053/j.ajkd.2013.01.027
13. Young A., Hodsman A. B., Boudville N., Geddes C., Gill J. [et al.]. Bone metabolism and fibroblast growth factor 23 levels after kidney donation . American Journal of kidney diseases. 2012;59(6):761-769. https://doi.org/10.1053/j.ajkd.2011.09.019
14. Mjoen G., Hallan S., Hartmann A., Foss A., Midtvedt K. [et al.]. Long-term risks for kidney donors. Kidney international. 2014;86(1):162-167. https://doi.org/10.1038/ki.2013.460
15. Segev D. L., Muzaale A. D., Caffo B. S., Mehta S. H., Singer A. L. [et al.]. Perioperative mortality and long-term survival following live kidney donation. JAMA. 2010;303(10):959-966. https://doi.org/10.1001/jama.2010.237
16. Muzaale A. D., Massie A. B., Wang M. C., Montgomery R. A., McBride M. A. [et al.]. Risk of end-stage renal disease following live kidney donation. JAMA. 2014;311(6):579-586. https://doi.org/10.100l/jama.2013.285141
17. Steiner R. W., Ix J. H., Rifkin D. E., Gert B. Estimating risks of de novo kidney diseases after living kidney donation. American Journal of Transplantation. 2014;14(3):538-544. https://doi.org/10.1111/ajt.12625
18. Lentine K. L., Schnitzler M. A., Xiao H., Axelrod D., Garg A. X. [et al.]. Consistency of racial variation in medical outcomes among publicly and privately insured living kidney donors. Transplantation. 2014;97(3);316-324.
https://doi.org/10.1097/01.TP.0000436731.23554.5e
19. Parsa A., Kao W. H., Xie D., Astor B. C., Li M., Hsu C. Y. [et al.]. APOL1 risk variants, race, and progression of chronic kidney disease The New England journal of medicine. 2013;369(23):2183-2196. https://doi.org/10.1056/NEJMoal 310345
20. Locke J. E., Reed R. D., Massie A., MacLennan P. A., Sawinski D. [et al.]. Obesity increases the risk of endstage renal disease among living kidney donors. Kidney International. 2017;91(3):699-703. https://doi.org/l0.1016/j.kint.2016.10.014
21. Mucsi I., Bansal A., Jeannette M., Famure O., Li Y. [et al.]. Mental Flealth and Behavioral Barriers in Access to Kidney Transplantation: A Canadian Cohort Study. Transplantation. 2017;101(6):1182-1190. https://doi.org/10.1097/TP.0000000000001362
22. Spital A. Ethical issues in living organ donation: Donor autonomy and beyond. American Journal of Kidney diseases. 2001;38(1):189-195. https://doi.org/l0.1053/ajkd.2001.25213
23. Tong A., Chapman J. R., Wong G., Kanellis J., McCarthy G., Craig J. C. The motivations and experiences of living kidney donors: A thematic synthesis. American Journal of Kidney Diseases. 2012;60(1):15-26. https://doi.org/l0.1053/j.ajkd.2011.11.043
24. World Health Assembly. Human organ transplantation (adopting the WHO Guiding Principles on Organ Transplantation): WHA44.25. World Health Organization, Geneva; 1991. Available at: www.who.int/transplantation/en/
25. Weale A. R., Lear P. A. Organ transplantation and the Human Tissue Act. Postgraduate Medical Journal. 2007;83(977):141-142. https://doi.org/10.1136/pgmj.2006.054213
26. Wright L., Faith K., Richardson R., Grant D. Ethical guidelines for the evaluation of living organ donors. Canadian Journal of Surgery. 2004;47(6):408-413. PMID: 15646438
27. Human Organ Transplants Act 1989. Available at: www.legislation.gov.uk/ukpga/1989/31/contents
28. Human Tissue Act 2004. Available at: www.legislation.gov.uk/ukpga/1989/31/contents
29. Antoine C., Legendre Ch. Organ Transplantation in France. Transplantation. 2017;101(3):445-448. https://doi.org/l0.1097/TP.0000000000001510
30. Agarwal S. K., Srivastava R. K., Gupta S., Tripathi S. Evolution of the Transplantation of Human Organ Act and law in India. Transplantation. 2012;94(2):110-113. https://doi.org/l0.1097/TP.0b013e31825acel5
31. Boratyriska M., Patrzalek D. Transplantology: Challenges for Today. Archivum Immunologiae et Therapiae Experimentali. 2016;64(1):37-45. https://doi.org/l0.1007/s00005-016-0439-1
32. Hafeez Bhatti A. B., Saud Dal F. Living Donor Liver Transplantation in Pakistan. Transplantation. 2017;101(7):1507-1508. https://doi.org/10.1097/TP.0000000000001737
33. Lavee J., Ashkenazi T., Stoler A., Cohen J., Beyar R. Preliminary Marked Increase in the National Organ Donation Rate in Israel Following Implementation of a New Organ Transplantation Law. American Journal of Transplantation. 2013;13(3):780-785. https://doi.org/10.llll/ajt.12001 34
34. Weimar W., Zuidema W., de Klerk M., Haase-Kromwijk B., Jzermans J. Altruistic kidney donation. Lancet. 2006;368(9540):987. https://doi.org/l0.1016/SO140-6736(06)69407-5
35. Alexander S. I., Clayton P. A., Chadban S. J. Organ Transplantation in Australia. Transplantation. 2017;101(5):891-892. https://doi.org/l0.1097/TP.0000000000001621
36. Roth A. E. Who Gets What and Why: The New Economics of Matchmaking and Market Design. Houghton Mifflin Harcourt, 2015.
37. Wall A. E., Veale J. L., Melcher M. L. Advanced Donation Programs and Deceased Donor-Initiated Chains-2 Innovations in Kidney Paired Donation. Transplantation. 2017;101(12):2818-2824. https://doi.org/10.1097/TP.0000000000001838
38. Toews M., Giancaspro M., Richards B., Ferrari P. Kidney Paired Donation and the «Valuable Consideration» Problem: The Experiences of Australia, Canada, and the United States. Transplantation. 2017;101(9):1996-2002. https://doi.org/10.1097/TP.0000000000001778
39. Kennedy C., Counihan A., Magee C. Transplantation in Ireland. Transplantation. 2017;101(1):1-4. https://doi.org/10.1097/TP.0000000000001479
40. Jochmans I., van Rosmalen M., Pirenne J., Samuel U. Adult Liver Allocation in Eurotransplant. Transplantation. 2017;101(7):1542-1550. https://doi.org/10.1097/TP.0000000000001631
41. Detry O., Van Deynse D., Van Vlierberghe H., Pirenne J. Organ Procurement and Transplantation in Belgium. Transplantation. 2017;101(9):1953-1955. https://doi.org/l0.1097/TP.0000000000001866
42. Fortin M. C., Buchman D., Wright L., Chandler J., Delaney S. [et al.]. Public Solicitation of Anonymous Organ Donors: A Position Paper by the Canadian Society of Transplantation. Transplantation. 2017;101(1);17-20. https://doi.org/10.1097/TP.0000000000001514
43. Mandelbrot D. A., Pavlakis M. Living donor practices in the United States. Advances in Chronic Kidney Disease. 2012;19(4):212-219. https://doi.org/10.1053/j.ackd.2012.04.010
44. Reshetnikov A. V. Institutional analysis in sociology of medicine. In: Sociology of medicine. Textbook. Moscow: GEOTAR-Media, 2016.

Keywords: living organ donation, organ donors, risk of organ donation


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy