Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
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ISSN 2073-8137

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Bone marrow aplasia in a patient treated with Cefotaxime

[Notes from practice]
Leonid Dvoretsky; Viktor Yakovlev; Margarita Suvorova; Elena Sergeeva; Georgii Zayratyants;

Description of the first case of aplastic anemia caused by сefotaxime, a third-generation сephalosporin, with lethal outcome is presented. Clinical record of a patient and post-mortem examination results are given. Possible mechanisms of cytopenias induced by сephalosporin antibiotics are discussed.


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Keywords: cephalosporin antibiotics, aplastic anemia, agranulocytosis

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy