of the North Caucasus
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Polymorphic variants of the TLR6 gene in adult patients with bronchial asthma
[Abstracts]
Lyudmila Barycheva; Liliya Shushanova; Alexandr Yagoda; Marina Golubeva; Milana Minasyan;
Immunogenetic studies were performed in 65 people with allergic bronchial asthma (BA) and 35 with non-allergic BA. This study established that the molecular genetic markers for an increased risk of allergic BA are allele TLR6 745C and TLR6 C745T. This association of polymorphic markers of the TLR6 gene is confirmed only for allergic BA. An increased
risk of allergic asthma was found in carriers of the common allele TLR6 745C and those with the heterozygous genotype C745T.
References:
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Keywords: bronchial asthma, Toll-like receptors, gene polymorphism
Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy