Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
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ISSN 2073-8137

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Study of pain in newborns

Alexandr Obedin; Alexandr Kachanov; Alina Mashchenko; Vladimir Pozharsky; Ekaterina Shmyreva; Igor Gerasimenko; Natalia Filipeva; Alena Voronova;

Evaluating the pain response in children is difficult. Nevertheless, the search for methods with which to assess pain objectively in newborns with surgical pathology of the digestive tract remains urgent. Therefore, we conducted a study of the serum concentrations of pain markers (substance P and neurokinin A) in infants to determine the relation of each of these indicators to pain-intensity scales (COMFORT, VAS). This objective evaluation of pain in newborns allowed the provision of individualized care to these and other infants with necrotizing enterocolitis at various stages of the disease.


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Keywords: pain, substance P, neurokinin A, COMFORT, VAS, NEC, newborns

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy