Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137

Site search

Correspondence address
310 Mira Street, Stavropol, Russia, 355017

+7 8652 352524; +7 8652 353229.

+7 8652 352524.


Morphological features of blood supply and innervation of the tooth pulp with caries of enamel and dentin

Sergey Sirak; Marina Vafiadi; Elena Neminushchaya; Irina Kopylova;

The article discusses the study of the microcirculatory system of the pulp of the tooth with caries of enamel and dentin. The study was conducted on 90 permanent teeth removed for surgical reasons and orthodontic indications, in patients aged 25 to 45 years. It is established that at the initial stages of caries of the enamel and dentin nerve changes of the pulp are mainly of a hypertrophic character. In the later stages of the disease, resorptive changes predominate. Changes in pulpal vessels during caries are already observed at the first signs of the disease, manifested by hyperemia and swelling. With the progression of caries, changes in the vessels go towards increasing the permeability of the vascular wall or its densification, coarsening with the formation at the postcapilar level of additional vascular anastomoses that are devoid of the adventitial membrane.


1. Orehova L. Yu., Kuchumova E. D., Styuf Y. V. Parodontologiya. – Parodontology. 2006;4:12-15.
2. Carmeliet P., Jain R. K. Nature. 2011;473(7347):298-307. doi: 10.1038/nature10144
3. Couve E., Osorio R., Schmachtenberg O. Journal of Dental Research. 2013;92(9):765-772. doi: 10.1177/0022034513495874
4. Grimm W. D., Arnold W. A., Sirak S. W. Journal of Clinical Periodontology. 2015;42(S17): 366b-366
5. Kim S. G. Dental Clinics of North America. 2017;61(1):127- 141. doi: 10.1016/j.cden.2016.08.005
6. Shchetinin E. V., Sirak S. V., Khodzhayan A. B. Medical News of North Caucasus. 2015;10(2):187-191. doi: 10.14300/mnnc.2015.10044
7. Sirak S. W., Entschladen F., Shchetinin E. W., Grimm W. D. Journal of Clinical Periodontology. 2015;42(S17):328a-328.
8. Smith A. J., Duncan H. F., Diogenes A., Simon S., Cooper P. R. Journal of Endodontics. 2016;42(1):47-56. doi: 10.1016/j.joen.2015.10.019
9. Tawfik H., Abu-Seida A. M., Hashem A. A., Nagy M. M. International Endodontic Journal. 2013;46(10):910-922. doi: 10.1111/iej.12079
10. Yadlapati M., Biguetti C., Cavalla F., Nieves F., Bessey C., Bohluli P., Garlet G. P., Letra A., Fakhouri W. D., Silva R. M. Journal of Endodontics, 2017;43(1):77-83. doi: 10.1016/j.joen.2016.09.022
11. Yoshiba K., Yoshiba N., Iwaku M. Endod. Dent. Traumatol. 2010;10:113-120.

Keywords: caries, dentin, enamel, blood supply, pulp

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy