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EBSCO

Clinical and immunological features in children with burn disease

[Pediatrics]
Vadim Ivanov; Maxim Razin; Vadim Svazyan; Yan Illek;

35 children (21 boys and 14 girls) with burn disease were included in the study. Patients were divided into groups depending on the outcome of thermal trauma: the study group consisted of 18 patients with favorable outcomes
of burn injury (the area of the body lesions was 34.6±2.3 %); comparison group – of 17 children with a fatal burn injury (burn area – 41.6±5.4 %). The severe burn injury in children was accompanied by substantial changes in the
blood plasma content of the general population of lymphocytes, cells with the phenotypes CD3, CD4, CD8 and CD19. Distinct immunological disorders in children with burn disease are an indication to intensify the antimicrobial therapy
accompanied by immunotherapy aimed at stimulating the cell immunity.

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Keywords: burn disease, immune disorders, diagnosis, treatment, children