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Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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The enzymatic defense mechanisms of the periodontium in experimental inflammation

[Stomatology]
Sergey Sirak; Natalia Bykova; Evgeny Shchetinin; Gregory Petrosyan; Nikolay Didenko; Oleg Tsymbalov;

The analysis of acid-alkaline status of blood and enzyme activity in periodontal tissues and mixed saliva of 130 white Wistar rats with experimental periodontitis was carried out. Metabolic acidosis with a shift of buffer bases in the acidic side was found. The application of glucosamine hydrochloride and chondroitin sulfate in the experimental inflammation of periodontal tissues results in normalization of acid-alkaline balance and activation of the protective mechanisms of the periodontal tissues manifested by an increase in antiglucuronidase and peroxidase activity aimed at the realization of antimicrobial function of the oral cavity.

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Keywords: inflammation, experiment, pаrodontitis, saliva, enzymes


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy