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A comprehensive examination of 114 patients with stage I and II hypertension was carried out. The aim of the study was to develop a modern, pathogenetically substantiated, comprehensive non-medicamentous method of curative correction of early cerebral manifestations of hypertension. The main correction of the initial manifestations
of hypertension was a special technique of curative gymnastics and respiratory gymnastics with elements of group psychotherapy. Group 1 (n=80) – patients who received complex non-drug treatment; Group 2 (n=34) – patients who received drug-induced antihypertensive therapy on the basis of monotherapy or low-dose combination therapy. Patients
of the 1 st group reported a significant (p<0.01) improvement after the end of treatment. Intergroup differences obtained before and after treatment, in patients of the 1 st and 2 nd groups it had a significant (p<0.01) nature. The study of cerebral hemodynamics significantly (p<0.01) indicated an increase in the majority of patients of the 1st
group of blood flow along the vertebral arteries, the posterior cerebral arteries. In the state of vasomotor reactivity and autoregulation of cerebral blood flow, there was significant (p<0.01) positive dynamics only in patients of the 1st group. Thus, the analysis of the results of our algorithm for treating patients with initial manifestations of hypertension,
conducted with the use of non-drug methods, demonstrates the validity of the proposed pathogenetic approach to ongoing therapy.
1. Aksenov V. A. Vlasov V. V. It is necessary to treat arterial hypertension 1 degrees? Therapy. 2016;1:58-66.
2. Baranova E. I. Treatment Arterial hypertension in special groups of patients (recommendation after treatment arterial hypertension 2,013 per year for European Society arterial hypertension and for European Society of Cardiology). Arterial hypertension.2014;20(1):38-44.
3. Dolgova I. N., Karpov S. M., Minaeva O. A., Kolesnikova E. V., Kalashjanc N. Z. Early neurophysiological signs of chronic cerebral ischemia. The journal of scientific articles Health and Education in the XXI eyelids. 2017; 19(6):42-44.
4. Dolgova I. N., Starodubzev A. I. Correction of chronic cerebrovascular disorders in patients with arterial hypertension. Medical news of the North Caucasus. 2011; 4(24):34-36.
5. Efremushkin G. G., Podsonnaja I. V. Hypertension and discirculatory encephalopathy – what comes first? CardioSomatiс. 2011;4:28-34.
6. Konradi A. O. Guidelines for the diagnosis and treatment of hypertension. The European society of hypertension. Handbook of outpatient physician.2004;6:3-10.
7. Kartashova E. A., Romantsov M. G., Sarvilina I. V. Influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension. Experimental and clinical pharmacology. 2014;77(6):18-23.
8. Melnik M. V., Shilov A. M. Hypertension and possibility of application of β-blockers. Farmateka. 2010;13:103-108.
9. Chen K. H., Yeh M. H., Livneh H., Chen B. C., Lin I. H. [et al.] Association of traditional Chinese medicine therapy and the risk of dementia in patients with hypertension: a nationwide population-based cohort study. BMC Complement Altern. Med. 2017;17(1):178. doi: 10.1186/s12906-017-1677-4
10. Coca A., Monteagudo E., Doménech M., Camafort M., Sierra C. Can the Treatment of Hypertension in the Middle-Aged Prevent Dementia in the Elderly? High Blood Press Cardiovasc. Prev. 2016;23(2):97-104. doi: 10.1007/s40292-016-0144-5
11. Jaroch J., Łoboz-Grudzień K., Magda S., Florescu M., Bociąga Z., [at. al.] The Relationship of Carotid Arterial Stiffness and Left Ventricular Concentric Hypertrophy in Hypertension. Adv.Clin. Exp. Med. 2016;25(2):263-272. doi: 10.17219/acem/34654
12. Kulshrestha M. Vidyanand. An analysis of the risk factors and the outcomes of cerebrovascular diseases in northern India.J ClinDiagn Res. 2013;7(1):127-131. doi: 10.7860/JCDR/2012/4918.2686
13. Liu J., Liu H., Zhao H., Shang G., Zhou Y. [at al.] Descriptive study of relationship between cardio-ankle vascular index and biomarkers in vascular-related diseases. Clin. Exp.Hypertens. 2017;25:1-5. doi:10.1080/10641963.2016.1273946
14. Ricci G., Pirillo I., Tomassoni D., Sirignano A., Grappasonni I. Metabolic syndrome, hypertension, and nervous system injury: Epidemiological correlates. Clin. Exp. Hypertens. 2017;39(1):8-16. doi: 10.1080/10641963. 2016.1210629
15. Rhéaume C., Leblanc M. E., Poirier P. Adiposity assessment: explaining the association between obesity, hypertension and stroke. Expert. Rev. Cardiovasc. Ther. 2011;9(12):1557-1564. doi: 10.1586/erc.11.167
16. Schusse C. M., Peterson A. L., Caplan J. P. Posterior reversible encephalopathy syndrome. Psychosomatics. 2013;54(3):205-11. doi: 10.1016/j.psym.2013.01.014
17. Sutin A. R., Scuteri A., Lakatta E. G., Tarasov K. V., Ferrucci L. [et al.] Trait antagonism and the progression of arterial thickening: women with antagonistic traits have similar carotid arterial thickness as men. Hypertension. 2010;56(4):617-622. doi: 10.1161/HYPERTENSIONAHA. 110.155317
18. Tocci G., Cicero A. F., Salvetti M., Musumeci M. B., Ferrucci A. [et al.] Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey. Clin. Hypertens. 2017;23:10. doi: 10.1186/s40885-017-0066-0
19. Vohr B. R., Allan W., Katz K. H., Schneider K. C., Ment L. R. Early predictors of hypertension in prematurely born adolescents. Acta Paediatr. 2010;99(12):1812-1818. doi: 10.1111/j.1651-2227.2010.01926.x
20. Wang Y., Xu J., Zhao X., Wang D., Wang C., Liu L. [et al.] Association of hypertension with stroke recurrence depends on ischemic stroke subtype. Stroke. 2013;44(5):1232-1237. doi: 10.1161/STROKEAHA. 111.000302
Keywords: arterial hypertension, therapy, combined therapy, nonmedical methods