Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137

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Efficiency of combined therapy of syndrome of the overlap between gastroesophageal reflux disease and functional dyspepsia

Irina Golub;

The effectiveness of treatment of patients with a syndrome of the overlap between gastroesophageal reflux disease and functional dyspepsia has been studied. Two groups of patients were formed: in the first group combination of prokinetic drug itoprid and proton pump inhibitor omeprazole was administered; in the second – only omeprazole.
After the course of treatment, a control study (24-hour electrogastrography and 24-hour pH-metry) was performed. The use of combination of itoprid and omeprazole significantly improved the condition of patients and parameters of myoelectric activity of the stomach, decreased the acid exposure of the esophagus.


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Keywords: gastroesophageal reflux disease, functional dyspepsia, overlap syndrome, myoelectric activity of stomach, itoprid, omeprazole

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy