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[CTD in adults]
Inna Viktorova; Nadezhda Konshu; Daria Ivanova;
Hypermobility of joints is one of the risk factors for osteoarthrosis. A tendency to family aggregation of joints hypermobility cases was registered. A genealogical study of probands suffering from osteoarthrosis accompanied by hypermobility of joints and their relatives of I, II, III degrees was carried out. We analyzed the pedigrees, determined the type of inheritance of joints hypermobility, the coefficient of heritability of predisposition to osteoarthrosis and index of family history burden. It was concluded that osteoarthrosis is multifactorial disorder associated with joint hypermobility.
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Keywords: hypermobility of joints, family, osteoarthrosis, syndrome of family hypermobility ща joints, connective tissue dysplasia