logo
Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
rus
русский
eng
english

Site search



Correspondence address
310 Mira Street, Stavropol, Russia, 355017

Tel
+7 865 2352511, +7 865 2353229.

E-mail
medvestnik@stgmu.ru

Osteoarthritis at patients with hyper mobility of joints: family studies

[CTD in adults]
Inna Viktorova; Nadezhda Konshu; Daria Ivanova;

Hypermobility of joints is one of the risk factors for osteoarthrosis. A tendency to family aggregation of joints hypermobility cases was registered. A genealogical study of probands suffering from osteoarthrosis accompanied by hypermobility of joints and their relatives of I, II, III degrees was carried out. We analyzed the pedigrees, determined the type of inheritance of joints hypermobility, the coefficient of heritability of predisposition to osteoarthrosis and index of family history burden. It was concluded that osteoarthrosis is multifactorial disorder associated with joint hypermobility.

Download

References:
1. Belenky A. G. Spravochnik poliklinicheskogo vracha. – Directory of outpatient physician. 2008;1:4-7.
2. Viktorova I. A., Konshu N. V., Kiseleva D. S. Spravochnik vracha obshchey praktiki. – Directory general practitioner. 2013;2:27-35.
3. Bravo J. F., Wolff C., Correa S. Ann. Rheum. Dis. 2007;66(2):244.
4. Mullick G., Bhakuni D.S., Shanmuganandan K., Garg M.K., Vasdev V., Kartik S., Jain R. Int. J. Rheum. Dis. 2013;16(5): 590-594. doi: 10.1111/1756-185x.12024.
5. De Paepe A., Malfait F. Clin. Genet. 2012;82(1):1-11. doi: 10.1111/j.1399-0004.2012.01858.x.
6. Falconer D. S. Ann. Hum. Genet. 1965;29:51-76. doi: 10.1111/j.1469-1809.1965.tb00500.x
7. Golightly Y. M., Nelson A. E., Kraus V. B., Renner J. B., Jordan J. M. Osteoarthritis Cartilage. 2012; 20:182. doi:10.1016/j.joca.2012.02.280
8. Grahame R., Bird H. A., Child A., Dolan A. L., Edwards- Fowler A., Ferrell W., Gurley-Green S., Keer R., Mansi E., Murray K. J., Smith E. J. Rheum. 2000;27(7):1777-1779.
9. Castori M., Camerota F., Celletti C., Danese C., Santilli V., Saraceni V. M., Grammatico P. Am. J. Med. Genet. A. 2010;152(3):556-564. doi: 10.1002/ajmg.a.33231.
10. Malfait F., Hakim A. J., De Paepe A., Grahame R. Rheumatology. 2006;45(5):502-507 doi:10.1093
11. Zweers M. C., Kucharekova M., Schalkwijk J. Ann. Rheum. Dis. 2005;64(3):504-505.

Keywords: hypermobility of joints, family, osteoarthrosis, syndrome of family hypermobility ща joints, connective tissue dysplasia


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy