of the North Caucasus
Series ПИ #ФС 77-26521.
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Histopathologcal features of parenchymal organs of laboratory animals with hypercoagulation syndrome
[Morphology]
Tatiana Bondar; Valentina Botasheva; Anna Muratovа; Andrey Sukhoveev; Alexander Vlasov; Kirill Svetlitskiy;
The histological features of parenchymal organs of laboratory rats with hypercoagulation at the 3rd trimester of pregnancy were investigated. In the liver parenchyma we revealed thrombi in the lumen of the central veins, swelling of hepatocytes and granular cytoplasm, decreasing of glycogen content in hepatocytes, degenerative changes in the liver cells, center-lobular liver necrosis; in the spleen tissue – infarction areas, demarcation zone with leukocyte infiltration at the periphery of infarction zone, anemia of red pulp.
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Keywords: hypercoagulation, hemostasis, hypoxia, liver and spleen parenchyma
Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy