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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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The influence of pinealectomy on psychotropic effect of adaptogenic drugs in rats

[Pharmacology]
Eduard Beyer; Anton Skornyakov; Eduard Arushanyan;

After administration of adaptogenic drugs of hormonal (melatonin 0,1 mg/kg) and vegetable origin (ginseng 100 mg/kg and bilobil 50 mg/kg) decrease of anxiety in open field and elevated plus maze and also improvement of memory in conditional passive avoidance test were observed. Melatonin had the most expressed optimizing effect on behavior of animals. After removal of pineal gland adaptogenic action of investigated drugs has been weakened.

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Keywords: adaptogenic drugs, pineal gland, behavior


Founders:
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