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https://doi.org/10.14300/mnnc.2026.00021

Oral microbiome status in patients with infertility: new aspects of an interdisciplinary issue

[Reviews]
Svetlana Iosifovna Gazhva; А.N. Sulima; Alexandra Viktorovna Em; V.A. Kucher; Yulia Gazhva; Artem Teterin;

This article analyzes the findings obtained through studies examining the oral microbiome in patients with reproductive
dysfunction. A comprehensive review of literature from the eLIBRARY.RU and CyberLeninka databases, as well as the
PubMed MEDLINE database, was conducted. This review synthesizes current understanding of the relationship between
oral dysbiosis and female infertility. Oral dysbiosis, particularly manifested as chronic periodontitis, acts as an additional
risk factor for infertility through mechanisms involving systemic inflammation and immune dysregulation.

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Keywords: oral cavity, microbiome, oral dysbiosis, infertility, association, interdisciplinary approach