• Main page
• About the journal
• Editorial board
• Subscription
• Information for contributors
• Editorial and Peer Review
• Issues archive
• Authors
• Articles
  • By alphabet
  • By category
• Blogs and comments

The journal is included into The list of leading scientific periodicals.

The journal is included into VINITI database and is registered in Electronic scientific library.

The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.

EBSCO

https://doi.org/10.14300/mnnc.2026.00001

Features of the metabolic status in young people, taking into account body weight

[Internal diseases]
Maria Evsevyeva; Oksana Sergeeva; I. I. Kolomoytseva; Elena Fursova; Angelica Rusidi; Nikolay Evgenyevich Hvatalin; Victoria Kudryavtseva; Irina Gachkova;

A total of 172 young individuals were examined at a Health and Anti-Aging Medicine Center, including 66 males and 106 females. All participants underwent assessment of major cardiovascular risk factors using a structured questionnaire, anthropometric examination with calculation of body mass index (BMI), and evaluation of metabolic status. Body weight categories were determined with consideration of sex-specific criteria. The metabolic status was assessed by lipid profile and capillary blood glucose levels.
It was found that the frequency of metabolic status disorders increased with increasing BM, while the severity and nature of the detected changes had gender differences. In girls, overweight and obesity were accompanied by an increase in the prevalence of dyslipidemia, an increase in the coefficient of atherogenicity and the formation of atherogenic combinations of lipid disorders. Similar changes in young men are statistically insignificant. In girls, the presence of links between BMI and lipid profile indicators was revealed, while in boys there were no correlations. Hyperglycemia was observed in individuals of both sexes in almost all BM variants, demonstrating the absence of dependence on BMI. The proportion of people with normal metabolic status decreased as the BM increased. However, with normal and insufficient BM, a significant prevalence of metabolic disorders remained. Thus, an increase in BM in young people is mainly associated with lipid metabolism disorders and is characterized by gender specificity.

Download

References:
1. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of population-based measurement studies. Lancet. 2024;403(10431):1027-1050. https://doi.org/10.1016/S0140-6736(23)02750-2
2. Lopez-Jimenez F., Di Cesare M., Powis J., Shrikhande S., Adeoye M. [et al.]. The weight of cardiovascular diseases: addressing the global cardiovascular crisis associated with obesity. Glob. Heart. 2025;20(1):68. https://doi.org/10.5334/gh.1451
3. Миргородская О. В., Голубев Н. А., Огрызко Е. В., Шелепова Е. А. Заболеваемость ожирением у детей в возрасте 0-17 лет в Российской Федерации в период с 2018 по 2023 год. Современные проблемы здравоохранения и медицинской статистики. 2024;(3):236-251. [Mirgorodskaya O. V., Golubev N. A., Ogryzko E. V., Shelepova E. A. Morbidity of obesity in children aged 0–17 years in the Russian Federation in the period 2018–2023. Sovremennye problemy zdravookhraneniya i medicinskoj statistiki. – Modern problems of health care and medical statistics. 2024;(3):236-251. (In Russ.)]. https://doi.org/10.24412/2312-2935-2024-3-236-251
4. Баланова Ю. А., Шальнова С. А., Имаева А. Э., Куценко В. А., Капустина А. В. [и др.]. Ожирение в российской
популяции: вклад в выживаемость и возникновение сердечно-сосудистых событий. Данные исследований ЭССЕ-РФ и ЭССЕ-РФ2. Кардиоваскулярная терапия и профилактика. 2025;24(6):22-34. [Balanova Yu. A., Shalnova S. A., Imaeva A. E., Kutsenko V. A., Kapustina A. V. [et al.]. Obesity in the Russian population: contribution to survival and cardiovascular events. Data
from the ESSE-RF and ESSE-RF2. Kardiovaskulyarnaya terapiya i profilaktika. – Cardiovascular Therapy and Prevention. 2025;24(6):22-34. (In Russ.)]. https://doi.org/10.15829/1728-8800-2025-4336
5. Chen T., Lin J., Lin Y., Xu L., Lu D. [et al.]. Effects of aerobic exercise and resistance exercise on physical
indexes and cardiovascular risk factors in obese and overweight school-age children: a systematic review and meta-analysis. PLoS One. 2021;16(9):e0257150. https://doi.org/10.1371/journal.pone.0257150
6. Chen Z., Zhou R., Liu X., Wang J., Wang L. [et al.]. Effects of aerobic exercise on blood lipids in people with
overweight or obesity: a systematic review and meta-analysis of randomized controlled trials. Life. 2025;15(2):166.
https://doi.org/10.3390/life15020166
7. Koliaki C., Liatis S., Kokkinos A. Obesity and cardiovascular disease: revisiting an old relationship. Metabolism.
2019;92:98-107. https://doi.org/10.1016/j.metabol.2018.10.011
8. Евсевьева М. Е., Кумукова З. В. Особенности психологического статуса у лиц молодого возраста с признаками артериальной гипертензии. Российский психиатрический журнал. 2007;(3):53-57. [Evsevieva M. E., Kumukova Z. V. Features of psychological status in young people with signs of arterial hypertension. Rossiyskiy psikhiatricheskiy zhurnal. – Russian Psychiatric Journal. 2007;(3):53-57. (In Russ.)].
9. Evsevieva M. E., Pshennikova M. G. Comparative assessment of different types of adaptational protection of the
myocardium during stress. Kardiologiia. 2002;42(4):51-54.
10. Visseren F. L. J., Mach F., Smulders Y. M., Carballo D., Koskinas K. C. [et al.]. 2021 ESC guidelines on cardiovascular disease prevention in clinical practice. Eur. Heart J. 2021;42(34):3227-3337.
https://doi.org/10.1093/eurheartj/ehab484
11. Xu L., Yang Q., Zhou J. Mechanisms of abnormal lipid metabolism in the pathogenesis of disease. Int. J. Mol. Sci.
2024;25(15):8465. https://doi.org/10.3390/ijms25158465
12. Kammar-García A., López-Moreno P., Hernández-Hernández M. E., Ortíz-Bueno A. M., Martínez-Montaño M. L. C.
Atherogenic index of plasma as a marker of cardiovascular risk factors in Mexicans aged 18 to 22 years. Proc. (Baylor
Univ. Med. Cent). 2020;34(1):22-27. https://doi.org/10.1080/08998280.2020.1799479
13. Assempoor R., Daneshvar M. S., Taghvaei A., Abroy A. S., Azimi A. [et al.]. Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies. Cardiovasc. Diabetol. 2025;24(1):35. https://doi.org/10.1186/s12933-025-02582-2
14. Ginsberg H. N., Packard C. J., Chapman M. J., Borén J., Aguilar-Salinas C. A. [et al.]. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies: a consensus statement from the European Atherosclerosis Society. Eur. Heart J. 2021;42(47):4791-4806.
https://doi.org/10.1093/eurheartj/ehab551
15. Shui X., Chen Z., Wen Z., Tang L., Tang W. [et al.]. Association of atherogenic index of plasma with angiographic
progression in patients with suspected coronary artery disease. Angiology. 2022;73(10):927-935. https://doi.org/10.1177/00033197221080911
16. Henderson M., Moore S. A., Harnois-Leblanc S., Johnston B. C., Fitzpatrick-Lewis D. [et al.]. Effectiveness of
behavioural and psychological interventions for managing obesity in children and adolescents: a systematic review
and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline. Pediatr. Obes. 2025;20(3):e13193. https://doi.org/10.1111/ijpo.13193
17. Zhang Y., Pan X. F., Chen J., Cao A., Zhang Y. [et al.]. Combined lifestyle factors and mortality. JAMA Netw.
Open. 2023;6(6):e2316714. https://doi.org/10.1001/jamanetworkopen.2023.16714
18. Бойцов С. А., Погосова Н. В., Аншелес А. А., Бадтиева В. А., Балахонова Т. В. [и др.]. Кардиоваскулярная
профилактика 2022. Российские национальные рекомендации. Российский кардиологический журнал. 2023;28(5):119-249. [Boytsov S. A., Pogosova N. V., Ansheles A. A., Badtieva V. A., Balakhonova T. V. [et al.]. Cardiovascular prevention 2022. Russian national guidelines. Rossiyskiy kardiologicheskiy zhurnal. – Russian Journal of Cardiology. 2023;28(5):119-249. (In Russ.)]. https://doi.org/10.15829/1560-4071-2023-5452
19. Golubnitschaja O., Liskova A., Koklesova L., Samec, M., Biringer, K. [et al.]. Caution, «normal» BMI: health
risks associated with potentially masked individual underweight-EPMA position paper 2021. EPMA J. 2021;12(3):243-264.
https://doi.org/10.1007/s13167-021-00251-4
20. Ежов М. В., Кухарчук В. В., Сергиенко И. В., Алиева А. С., Анциферов М. Б. [и др.]. Нарушения липидного обмена. Клинические рекомендации 2023. Российский кардиологический журнал. 2023;28(5):5471. [Ezhov M. V., Kukharchuk V. V., Sergienko I. V., Alieva A. S., Antsiferov M. B. [et al.]. Disorders of lipid metabolism. Clinical Guidelines 2023. Rossiyskiy kardiologicheskiy zhurnal. – Russian Journal of Cardiology. 2023;28(5):5471. (In Russ.)]. https://doi.org/10.15829/1560-4071-2023-5471
21. Al Dhaheri A. S., Mohamad M. N., Jarrar A. H., Ohuma E. O., Ismail L. C. [et al.]. A cross-sectional study of the prevalence of metabolic syndrome among young female Emirati adults. PLoS One. 2016;11(7):e0159378.
https://doi.org/10.1371/journal.pone.0159378
22. Zheng K., Yan Y., Ma L., Liu R., Zhao T. [et al.]. Sex difference in the relationship between childhood obesity and
abnormal lipid profiles in young adults. BMC Endocr. Disord. 2025;25:44. https://doi.org/10.1186/s12902-025-01859-7
23. Chen N., Hu L. K., Sun Y., Dong J., Chu X. [et al.]. Associations of waist-to-height ratio with the incidence of
type 2 diabetes and mediation analysis: two independent cohort studies. Obes. Res. Clin. Pract. 2023;17(1):9-15.
https://doi.org/10.1016/j.orcp.2022.12.005
24. Raposeiras-Roubin S., Rosselló X., Oliva B., Fernández-Friera L., Mendiguren J. M. [et al.]. Triglycerides
and residual atherosclerotic risk. J. Am. Coll. Cardiol. 2021;77(24):3031-3041. https://doi.org/10.1016/j.jacc.2021.04.059
25. Nolan P. B., Carrick-Ranson G., Stinear J. W., Reading S. A., Dalleck L. C. Prevalence of metabolic syndrome
and metabolic syndrome components in young adults: a pooled analysis. Prev. Med. Rep. 2017;7:211-215.
https://doi.org/10.1016/j.pmedr.2017.07.004
26. Sun Q., Wang J., Wang H., Yu H., Wan K. [et al.]. Effect of long-term taurine supplementation on the lipid and glycaemic profile in adults with overweight or obesity: a systematic review and meta-analysis. Nutrients. 2024;17(1):55.
https://doi.org/10.3390/nu17010055
27. Farhangi M. A., Vajdi M., Fathollahi P. Dietary total antioxidant capacity (TAC), general and central obesity
indices and serum lipids among adults: an updated systematic review and meta-analysis. Int. J. Vitam. Nutr.
Res. 2022;92(5-6):406-422. https://doi.org/10.1024/0300-9831/a000675
28. Hadi A., Pourmasoumi M., Najafgholizadeh A., Clark C. C. T., Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC
Complement. Med. Ther. 2021;21(1):179. https://doi.org/10.1186/s12906-021-03351-w

Keywords: body weight, body mass index, dyslipidemia, hyperglycemia, metabolic status, young adults