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Using of silver nanoparticles in current experimental medicine and clinical practice

[Reviews]
Vadim Vladimirovich Malyshko; Ilya Bykov; Timofey Anatolyevich Zaikin; Denis Igorevich Shashkov; Arkady Viktorovich Moiseev; Alexander Basov; Elena Evgenevna Esaulenko; Aleksandr Storozhuk;

The use of silver nanoparticles (AgNPs) in clinical practice and experimental medicine is of significant interest due to their pronounced antiviral, microbicidal, fungicidal and antitumor effects. The ability of AgNPs to exert varying intensity effects on biological objects is determined by their size (usually less than 100 nm), shape (spherical, triangular, rod-shaped, etc.), structure of the outer layers (depending on the type of ligand), charge (positive, negative, almost neutral). It has been shown that nanoclusters with a diameter of up to 30 nm are in demand in surgery, oncology, dentistry, traumatology, and laboratory diagnostics, which allows for a broader understanding of the possibilities of using such innovative nanotechnologies.

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Keywords: silver nanoparticles, antibacterial activity, experimental medicine, ligand, nanoparticle synthesis, cytotoxicity


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy