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ISSN 2073-8137
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Local pharyngeal AL -amyloidosis with laryngeal lesion. Clinical case

[Notes from practice]
Andrey Evgenievich Orlov; Oleg Igorevich Kaganov; Aleksandr Aleksandrovich Makhonin; Maria Mikhailovna Bondarenko; Magomed Gadzhievich Gadzhiev;

The article presents a clinical observation of local pharyngeal amyloidosis in a patient examined and treated at the Department of Head and Neck Tumors (Public Budgetary Healthcare Institution «Regional Clinical Oncological Dispensary»). The clinical case serves proof to the need for further research to be carried out focusing on this disease, as well as reveals a need to implement advanced technologies for diagnosing and treating amyloidosis.

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References:
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2. Lysenko (Kozlovskaya) L. V., Rameev V. V., Moiseev S. V., Blagova O. V., Bogdanova E. I. [et al.]. Clinical recommendations for the diagnosis and treatment of systemic amyloidosis. Klinicheskaya farmakologiyai terapiya. – Clinical pharmacology and therapy. 2020;1:13-24. (In Russ.). https://doi.org/10.32756/0869-5490-2020-1-13-24
3. Guselnikova V. V., Sufieva D. A., Tsyba D. L., Korzhevsky D. E. The use of histochemical dyes for the fluorescent detection of amyloid clusters in human tissues. Vestnik RSMU. 2021;4. (In Russ.). https://doi.org/10.24075/vrgmu.2021.034
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5. Kryachok I. A., Stepanishina Ya. A. AL-Amyloidosis: Complexities and Perspectives. Klinicheskaya onkologiya. – Clinical Oncology. 2019;1(33). (In Russ.). https://doi.org/10.32471/clinicaloncology.2663466x.38.22357
6. Benson M. D., Buxbaum J. N., Eisenberg D. S., Merlini G., Saraiva M. J. M. [et al.]. Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee. Amyloid. 2020;27(4):217-222. https://doi.org/10.1080/13506129.2020.1835263
7. Bertelsen C., Chadwick K., Holland J., Flint P., Schindler J. S. Long-term follow-up after radiation therapy for laryngeal amyloidosis. The Laryngoscope. 2021;131(8):1810-1815. https://doi.org/10.1002/lary.29061
8. Send T., Spiegel J. L., Schade G., Pantelis A., Olthoff A. [et al.]. Amyloidosis of the upper aerodigestive tract: management of a rare disease and review of the literature. Dysphagia. 2019;34(2):179-191. https://doi.org/10.1007/s00455-018-9956-x

Keywords: local AL-amyloidosis, amyloidosis of the upper respiratory tract, nasopharynx, oropharynx, larynx


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