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https://doi.org/10.14300/mnnc.2024.19057

Surgical treatment for thyroid diseases in children

[Abstracts]
Sergey Minaev; Igor Gerasimenko; Oksana Igorevna Iachnaia;

The outcomes of treating thyroid nodules were studied in 62 children, with girls predominating (74.2 %). The patients were divided into two groups: the main group (25) and the control group (37). In the main group, a specifically developed technique of platelet rich plasma (PRP) was used intraoperatively. In the postoperative period, the pain syndrome was relieved reliably (p<0.01) faster in the main group if compared with the control (18.6±1.5 and 42.2±3.6 hours, respectively). The hospitalization duration for the main group was two bed-days shorter if matched VS the control group. The intraoperative use of PRP by the layer-by-layer infiltration method after intervention performed on the thyroid gland shortens the patient’s rehabilitation period as well as it reduces the risk of complications in the postoperative period.

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References:
1. Sandy J. L., Titmuss A., Hameed S., Cho Y. H. Sandler G. [et al.]. Thyroid nodules in children and adolescents: Investigation and management. J. Paediatr. Child. Health. 2022;58(12):2163-2168. https://doi.org/10.1111/jpc.16257
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3. Allen N., Desai N., Song C., Yu J., Prasad U. [et al.]. Clinical features may help to identify children and adolescents with greatest risk for thyroid nodules. J. Endocrinol. Invest. 2020;43(7):925-934. https://doi.org/10.1007/s40618-019-01176-6
4. Vladimirova O. V., Minaev S. V., Gerasimenko I. N., Yachnaya O. I., Timofeev S. I. [et al.]. Method of using thrombocyte-rich autoplasma in thyroidectomy or hemistrumectomy, involving treating surgical site with antiseptic solution, performing Kocher approach. Patent № 2815759 C1 Russian Federation, IPC A61B 17/06, A61K 35/19, A61P 17/02: № 2023107363: application. 03/27/2023: publ. 03/21/2024.
5. Minaev S. V., Timofeev S. I., Grigorova A. N., Vladimirova O. V., Bolotov Yu. N. [et al.]. Platelet-rich plasma in surgical practice: a review. Rossijskij vestnik detskoj hirurgii, anesteziologii i reanimatologii. – Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care.2023;13(3):405-417. (In Russ.). https://doi.org/10.17816/psaic1508

Keywords: hyroid nodules, platelet-rich plasma, outcomes, children