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[Abstracts]
Olga Vladimirovna Gekkieva; Roman Aleksandrovich Kozetinsky; Irina Valerievna Tregubova; Alexandr Obedin;
The results of a comparative assessment of the effectiveness of early surfactant administration in cancer patients after surgery with an uncomplicated course of the postoperative period are presented. The use of the drug accelerated the oxygenation processes of patients with a reduced risk of nosocomial pneumonia
References:
1. Rosenberg O. A. Pulmonary surfactant preparations and ARDS surfactant therapy in surgical intensive care (literature review). Kreativnaia hirurgiia i onkologiia. – Creative surgery and oncology. 2019;9(1):50-65. (In Russ.). https://doi.org/10.24060/2076-3093-2019-9-1-50-65
2. Daniher D., McCaig L., Yuqing Ye., Veldhuizen R., Lewis J. [et al.]. Protective effects of aerosolized pulmonary surfactant powder in a model of ventilator-induced lung injury. Int. J. Pharm. 2020;583:119359. https://doi.org/10.1016/j.ijpharm.2020.119359
3. Hentschel R., Bohlin K., van Kaam A., Fuchs H., Danhaive O. Surfactant replacement therapy: from biological basis to current clinical practice. Pediatr. Res. 2020;88(2):176-183. https://doi.org/10.1038/s41390-020-0750-8
4. Pérez-Gil J. A recipe for a good clinical pulmonary surfactant. Biomed. J. 2022;45(4):615-628. https://doi.org/10.1016/j.bj.2022.03.001
5. Gekkieva O. V., Kozetinsky R. A., Tregubova I. B. Surfactant-BL in the complex treatment of acute respiratory failure in cancer patients who underwent surgical interventions on the organs of the thoracic cavity. Efferentnaya terapiya. – Efferent therapy. 2013;19(2):101- 102. (In Russ.).
Keywords: surfactant, cancer patients, postoperative period