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Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Evaluation of short-term outcomes in preterm infants with necrotizing enterocolitis

[Abstracts]
Igor Gerasimenko; Alexandr Obedin; Sergey Timofeev; Alesya Isaeva; Alina Nikolaevna Grigorova; Dmitry Nikolaevich Mashchenko; Oksana Igorevna Iachnaia; Anastasia Alekseevna Lytkina;

The work assessed the impact of the principles of open resuscitation on the results of the treatment of premature infants with NEC. The type of organization of the ICU (open or limited access) did not affect the daily and 7-day mortality. The previous severity of the NEC condition and the nature of the surgical intervention were of primary importance. Significant differences were noted in terms of the duration of administration of systemic analgesics (2.3+1.1 and 6.8+1.2 days, p<0.05) and the timing of the start of enteral nutrition (3.7+1.5 and 6.7+2.2 days, p<0.05). With unrestricted access of mothers of newborns with NEC to ICU, the microbial spectrum in cultures from different loci was significantly richer. However, further research is needed to explore this approach in preterm infants with NEC

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References:
1. Hackam D. J., Sodhi C. P. Bench to bedside – new insights into the pathogenesis of necrotizing enterocolitis. Nat. Rev. Gastroenterol. Hepatol. 2022;19(7):468-479. https://doi.org/10.1038/s41575-022-00594-x
2. Veshkurtseva I. M., Akselrov M. A., Minaev S. V., Suprunets S. N., Emelyanova V. A. [et al.] Effect of microbial landscape on the character of antibacterial therapy in newborns with necrotizing enterocolitis. Medical News of North Caucasus. 2020;15(4):492-495. https://doi.org/10.14300/mnnc.2020.15115
3. Tarakanov V. A., Minaev S. V., Kolesnikov E. G., Korotkov K. G., Abushkevich V. G. [et al.] Topical diagnosis of the boundaries of necrotic segment of the small intestine in the high frequency electromagnetic fields. Medical News of North Caucasus. 2019;14(2):308-311. https://doi.org/10.14300/mnnc.2019.14074
4. Mistraletti G., Giannini A., Gristina G., Malacarne P., Mazzon D. [et al.] Why and how to open intensive care units to family visits during the pandemic. Crit. Care. 2021;25(1):191. https://doi.org/10.1186/s13054-021-03608-3
5. Li W., Tang J., Zhu Z., Tang W. Initial surgical treatment of necrotizing enterocolitis: a meta-analysis of peritoneal drainage versus laparotomy. Eur. J. Pediatr. 2022;181(7):2593-2601. https://doi.org/10.1007/s00431-022-04454-3

Keywords: preterm infants, necrotizing enterocolitis, open visitation, outcomes


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