• Main page
• About the journal
• Editorial board
• Subscription
• Information for contributors
• Editorial and Peer Review
• Issues archive
• Authors
• Articles
  • By alphabet
  • By category
• Blogs and comments

The journal is included into The list of leading scientific periodicals.

The journal is included into VINITI database and is registered in Electronic scientific library.

The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.

EBSCO

https://doi.org/10.14300/mnnc.2023.18026

Possibilities of modern technologies in the treatment of injuries and fistulas of the esophagus

[Reviews]
Damir Abdulovich Demaldinov; Robert Mustafin; Yulia Molchanova;

By the nature of the occurrence, complete defects of the esophageal wall are divided into ruptures, perforations and anastomoses failure after surgery. Traditional surgical methods of treatment are technically complicated and have low efficiency. Modern endoscopic technologies have made it possible to achieve significant progress in the treatment of this pathology. Endoscopic vacuum therapy (EVT) appears to be the most promising approach. This method, based on the use of negative pressure, is an endoscopic introduction of the drainage material on a special probe into the lumen of the defect. In this review, we have tried to summarize the mechanisms of action, existing techniques, efficacy and safety of vacuum therapy for esophageal defects of various etiologies.

Download

References:
1. Mureșan M., Mureșan S., Balmoș I., Sala D., Suciu B., Torok A. Sepsis in acute mediastinitis – a severe complication after oesophageal perforations. A review of the literature. J. Crit. Care Med. (Targu Mures). 2019;5(2):49-55. https://doi.org/10.2478/jccm-2019-0008
2. Kulish P. A., Popov A. Y., Porkhanov V. A., Baryshev A. G., Slavinsky V. G. [еt al.]. Immediate results of treatment of patients with penetrating defects of the esophageal wall by the method of endoscopic vacuum drainage. Innovacionnaja medicina Kubani. – Innovative medicine of the Kuban. 2016;(2):27-34. (In Russ.).
3. Shaimardanov R. Sh., Gubaev R. F., Khamzin I. I., Gafurov K. D., Khisamiev I. G. [еt al.]. Spontaneous esophagus rupture treatment by endoscopic stenting (clinical case). Vestnik sovremennoj klinicheskoj mediciny. – Bulletin of modern clinical medicine. 2018;11(5):181-185. (In Russ.). https://doi.org/10.20969/vskm.2018.11(5).181-185
4. Kotiv B. N., Dzidzava I. I., Brednev A. O., Fufaev E. E., Belevich V. L. [еt al.]. Minimally invasive methods in treatment of spontaneous esophageal rupture. Novosti hirurgii. – Surgery news. 2015;23(4):467-473. (In Russ.). https://doi.org/10.18484/2305-0047.2015.4.467
5. Starkov Yu. G., Vyborny M. I., Ruchkin D. V., Dzhantukhanova D. V., Zamolodchikov R. D., Vorobieva V. A. Endoscopic treatment of esophageal anastomoses leakage using a vacuum-aspiration system. Hirurgija. Zhurnal imeni N. I. Pirogova. – Surgery. Journal named after N. I. Pirogov. 2019;10:13-20. (In Russ.). https://doi.org/10.17116/hirurgia2019101
6. Brednev A. O., Kotiv B. N., Dzidzawa I. I. Esophageal injuries: diagnosis and modern tactics of treatment. Vestnik voenno-medicinskoj akademii. – Bulletin of the Military Medical Academy. 2015;3(51):255-260. (In Russ.).
7. Halliday E., Patel A., Hindmarsh A., Sujendran V. Iatrogenic oesophageal perforation during placement of an endoscopic vacuum therapy device. J. Surg. Case Rep. 2016;2016(7):1-4. https://doi.org/10.1093/jscr/rjw131
8. Loske G., Schorsch T., Dahm C., Martens E., Müller C. Iatrogenic perforation of oesophagus successfully treated with Endoscopic Vacuum Therapy (EVT). Endosc. Int. Open. 2015;3(6):547-551. https://doi.org/10.1055/s-0034-1392566
9. Zhang C. C., Liesenfeld L., Klotz R., Koschny R., Rupp C. [еt al.]. Feasibility, effectiveness, and safety of endoscopic vacuum therapy for intrathoracic anastomotic leakage following transthoracic esophageal resection. BMC Gastroenterol. 2021;21(1):72. https://doi.org/10.1186/s12876-021-01651-6
10. de Moura D. T. H., de Moura B. F. B. H., Manfredi M. A., Hathorn K. E., Bazarbashi A. N. [еt al.]. Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects. World J. Gastrointest. Endosc. 2019;11(5):329-344. https://doi.org/10.4253/wjge.v11.i5.329
11. Möschler O., Nies C., Mueller M. K. Endoscopic vacuum therapy for esophageal perforation and leakage. Endosc. Int. Open. 2015;3(6):554-558. https://doi.org/10.1055/s-0034-1392568
12. Rubicondo C., Lovece A., Pinelli D., Indriolo A., Lucianetti A., Colledan M. Endoluminal vacuum-assisted closure (E-Vac) therapy for postoperative esophageal fistula: successful case series and literature review. World J. Surg. Oncol. 2020;18(1):301. https://doi.org/10.1186/s12957-020-02073-6
13. Di Leo M., Maselli R., Ferrara E. C., Poliani L., Al Awadhi S., Repici A. Endoscopic management of benign esophageal ruptures and leaks. Curr. Treat. Options Gastroenterol. 2017;15(2):268-284. https://doi.org/10.1007/s11938-017-0138-y
14. Godin A., Liberman M. The modern approach to esophageal palliative and emergency surgery. Ann. Transl. Med. 2021;9(10):905. https://doi.org/10.21037/atm.2020.03.107
15. Kim J. H., Park J. J., Jung I. W., Kim S. H., Kim H. D. [et al.] Treatment of traumatic esophagopleural fistula using the Over-the-Scope-Clip System. Clin. Endosc. 2015;48(5):440-443. https://doi.org/10.5946/ce.2015.48.5.440
16. Иванов А. И., Бурмистров М. В., Попов В. А., Сигал Е. И., Сигал А. М. Эндоскопическое лечение перфораций пищевода и несостоятельности анастомозов. Практическая медицина. 2019;17(6):74-80. https://doi.org/10.32000/2072-1757-2019-6-74-80
17. Chon S. H., Bartella I., Bürger M., Rieck I., Goeser T. [еt al.] VACS-tent: a new option for endoscopic vacuum therapy in patients with esophageal anastomotic leaks after upper gastrointestinal surgery. Endoscopy. 2020;52(5):166-167. https://doi.org/10.1055/a-1047-0244
18. Lange J., Dormann A., Bulian D. R., Hügle U., Eisenberger C. F., Heiss M. M. VACS-tent: Combining the bene fits of endoscopic vacuum therapy and covered stents for upper gastrointestinal tract leakage. Endosc. Int. Open. 2021;9(6):971-976. https://doi.org/10.1055/a-1474-9932
19. Panayi A. C., Leavitt T., Orgill D. P. Evidence based review of negative pressure wound therapy. World J. Dermatology. 2017;6(1):1-16. https://doi.org/10.5314/wjd.v6.i1.1
20. Lee D. K., Min Y. W. Role of endoscopic vacuum therapy as a treatment for anastomosis leak after esophageal cancer surgery. Korean J. Thorac. Cardiovasc. Surg. 2020;53(4):205-210. https://doi.org/10.5090/kjtcs.2020.53.4.205
21. de Moura D. T. H., Brunaldi V. O., Minata M., Riccioppo D., Santo M. A., de Moura E. G. H. Endoscopic vacuum therapy for a large esophageal perforation after bariatric stent placement. VideoGIE. 2018;3(11):346-348. https://doi.org/10.1016/j.vgie.2018.08.009
22. Loske G., Schorsch T., Rucktaeschel F., Schulze W., Riefel B. [еt al.] Open-pore film drainage (OFD): a new multipurpose tool for endoscopic negative pressure therapy (ENPT). Endosc. Int. Open. 2018;6(7):865-871. https://doi.org/10.1055/a-0599-5886
23. Rinchinov V. P., Plehanov A. N., Cibikdorzhiev B. D., Sultunov T. V., Gavrilova A. K. Pervyi opyt primenenija iendoskopicheskoj vakuumno aspiracionnoi terapii v lechenii spontannogo razryva pishhevoda (sindrom Burhave). Bjulleten’ VSNC SO RAMN. – Bulletin VSNTS SB RAMS. 2017;2(1):136-140. (In Russ.).
24. Fraga J. C., Nunes D. L., Andreolio C., Ferreira J., Holanda F. [et al.]. Endoscopic vacuum sponge therapy for an infant with an esophageal leak. J. Thorac. Cardiovasc. Surg. 2018;156(5):193-195. https://doi.org/10.1016/j.jtcvs.2018.04.061
25. Park S., Son B. S., Park H., Kim H. J., Park S. J., Kim H. Y. Endoscopic vacuum therapy for cervical leakage following esophagectomy under monitored anesthesia care: a case report. Ann. Palliat. Med. 2021;10(4):4906-4910. https://doi.org/10.21037/apm-20-1394
26. Morais R., Vilas-Boas F., Silva M., Pereira P., Macedo G. Endoscopic vacuum therapy for esophageal perforation treatment after foreign body ingestion: resolution after a single session. GE Port. J. Gastroenterol. 2020;27(3):207-209. https://doi.org/10.1159/000503011
27. Khatkov I. E., Shishin K. V., Nedoluzhko I. Yu., Kurushkina N. A., Izrailov R. E. [еt al.]. Endoscopic vacuum therapy in the treatment of anastomotic leak in the upper gastrointestinal tract. First experience and review of literature. Jendoskopicheskaja hirurgija. – Endoscopic surgery. 2016;22(2):3-9. (In Russ.). https://doi.org/10.17116/endoskop20162223-9
28. de Pasqual C. A., Mengardo V., Tomba F., Veltri A., Sacco M. [еt al.]. Effectiveness of endoscopic vacuumtherapy as rescue treatment in factory leaks after gastroesophageal surgery. Updates Surg. 2021;73(2):607-614. https://doi.org/10.1007/s13304-020-00935-y
29. Eichelmann A.-K., Ismail S., Merten J., Slepecka P., Palmes D. [еt al.]. Economic burden of endoscopic vacuum therapy compared to alternative therapy methods in patients with anastomotic leakage after esophagectomy. J. Gastrointest. Surg. 2021;25(10):2447-2454. https://doi.org/10.1007/s11605-021-04955-w
30. Heits N., Stapel L., Reichert B., Schafmayer C., Schniewind B. [еt al.]. Endoscopic endoluminal vacuum therapy in esophageal perforation. Ann. Thorac. Surg. 2014;97(3):1029-1035. https://doi.org/10.1016/j.athoracsur.2013.11.014
31. Mastoridis S., Chana P., Singh M., Akbari K., Shalaby S. [еt al.]. Endoscopic vacuum therapy (EVT) in the management. Endoscopic vacuum therapy (EVT) in the management of esophageal perforations and post-operative leaks. Minim. Invasive Ther. Allied Technol. 2020;10:1-9. https://doi.org/10.1080/13645706.2020
32. Ooi G., Burton P., Packiyanathan A., Loh D., Chen R. [еt al.]. Indications and efficacy of endoscopic vacuumassisted closure therapy for upper gastrointestinal perforations. ANZ J. Surg. 2018;88(4):257-263. https://doi.org/10.1111/ans.13837
33. Lenzen H., Negm A. A., Erichsen T. J., Manns M. P., Wedemeyer J., Lankisch T. O. Successful treatment of cervical esophageal leakage by endoscopic-vacuum assisted closure therapy. World J. Gastrointest. Endosc. 2013;5(7):340-345. https://doi.org/10.4253/wjge.v5.i7.340
34. Walsh L. T., Loloi J., Manzo C. E., Mathew A., Maranki J. [еt al.]. Successful treatment of large cavity esophageal disrupshion with transluminal washout and endoscopic vacuum therapy: a report of two cases. Ther. Adv. Gastrointest. Endosc. 2019;12:1-6. https://doi.org/10.1177/2631774519860300
35. Mennigen R., Harting C., Lindner K., Vowinkel T., Rijcken E. [еt al.]. Comparison of endoscopic vacuum therapy versus stent for anastomotic leak after esophagectomy. J. Gastrointest. Surg. 2015;19(7):1229-1235. https://doi.org/10.1007/s11605-015-2847-7
36. Pournaras D. J., Hardwick R. H., Safranek P. M., Sujendran V., Bennett J. [еt al.]. Endoluminal vacuum therapy (e-vac): a treatment option in oesophagogastric surgery. World J. Surg. 2018;42(8):2507-2511. https://doi.org/10.1007/s00268-018-4463-7
37. Brangewitz M., Voigtländer T., Helfritz F. A., Lankisch T. O., Winkler M. [еt al.]. Endoscopic closure of esophageal intrathoracic leaks: stent versus endoscopic vacuumassisted closure, a retrospective analysis. Endoscopy. 2013;45(6):433-438. https://doi.org/10.1055/s-0032-1326435
38. Schniewind B., Schafmayer C., Voehrs G., Egberts J., von Schoenfels W. [еt al.]. Endoscopic endoluminal vacuum therapy is superior to other regimens in managing anastomotic leakage after esophagectomy: a comparative retrospective study. Surg. Endosc. 2013;27(10):3883-3890. https://doi.org/10.1007/s00464-013-2998-0
39. Min Y. W., Kim T., Lee H., Min B. H., Kim H. K. [еt al.]. Endoscopic vacuum therapy for postoperative esophageal leak. BMC Surg. 2019;19(1):37. https://doi.org/10.1186/s12893-019-0497-5
40. Noh S. M., Ahn J. Y., Lee J. H., Jung H. Y., Al Ghamdi Z. [еt al.]. Endoscopic vacuum-assisted closure therapy in patient with anastomotic leakage after esophagectomy: a single center experience. Gastroenterol. Res. Pract. 2018;2018:1-7. https://doi.org/10.1155/2018/1697968
41. Bludau M., Hölscher A. H., Herbold T., Leers J. M., Gutschow C. [еt al.]. Management of upper intestinal leaks using an endoscopic vacuum-assisted closure system (E-VAC). Surg. Endosc. 2014;28(3):896-901. https://doi.org/10.1007/s00464-013-3244-5
42. Still S., Mencio M., Ontiveros E., Burdick J., Leeds S. G. Primary and rescue endoluminal vacuum therapy in the management of esophageal perforations and leaks. Ann. Thorac. Cardiovasc. Surg. 2018;24(4):173-179. https://doi.org/10.5761/atcs.oa.17-00107
43. Bludau M., Fuchs H. F., Herbold T., Maus M. K. H., Alakus H. [еt al.]. Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks. Surg. Endosc. 2018;32(4):1906-1914. https://doi.org/10.1007/s00464-017-5883-4
44. Schorsch T., Müller C., Loske G. Endoscopic vacuum therapy of perforations and anastomotic insufficiency of the esophagus. Chirurg. 2014;85(12):1081-1093. https://doi.org/10.1007/s00104-014-2764-4
45. Laukoetter M. G., Mennigen R., Neumann P. A., Dhayat S., Horst G. [еt al.]. Successful closure of defects in the upper gastrointestinal tract by endoscopic vacuum therapy (EVT): a prospective cohort study. Surg. Endosc. 2017;31(6):2687-2696. https://doi.org/10.1007/s00464-016-5265-3
46. Kuehn F., Schiffmann L., Janisch F., Schwandner F., Alsfasser G. [еt al.]. Surgical endoscopic vacuum therapy for defects of the upper gastrointestinal tract. J. Gastrointest. Surg. 2016;20(2):237-243. https://doi.org/10.1007/s11605-015-3044-4
47. Ward M. A., Hassan T., Burdick J. S., Leeds S. G. Endoscopic vacuum assisted wound closure (EVAC) device to treat esophageal and gastric leaks: assessing time to proficiency and cost. Surg. Endosc. 2019;33(12):3970-3975. https://doi.org/10.1007/s00464-019-06685-2
48. Eichelmann A. K., Ismail S., Merten J., Slepecka P., Palmes D. [еt al.]. Economic burden of endoscopic vacuum therapy compared to alternative therapy methods in patients with anastomotic leakage after esophagectomy. J. Gastrointest. Surg. 2021. https://doi.org/10.1007/s11605-021-04955-w
49. Dhayat S. A., Schacht R., Mennigen R., Palmes D., Vogel T. [еt al.]. Long-term assessment of the quality of life after successful endoscopic vacuum therapy of defects of the upper gastrointestinal tract Quality of life after EVT. J. Gastrointest. Surg. 2019;23(2):280-287. https://doi.org/10.1007/s11605-018-4038-9
50. Berlth F., Bludau M., Plum P. S., Herbold T., Christ H. [еt al.]. Self-expanding metal stents versus endoscopic vacuum therapy in anastomotic leak treatment after oncologic gastroesophageal surgery. J. Gastrointest. Surg. 2019;23(1):67-75. https://doi.org/10.1007/s11605-018-4000-x
51. Tachezy M., Chon S. H., Rieck I., Kantowski M., Christ H. [еt al.]. Endoscopic vacuum therapy versus stent treatment of esophageal anastomotic leaks (ESOLEAK): study protocol for a prospective randomized phase 2 trial. Trials. 2021;22(1):377. https://doi.org/10.1186/s13063-021-05315-4
52. Verstegen M. H. P., Bouwense S. A. W., van Workum F., Ten Broek R., Siersema P. D. [еt al.]. Management of intrathoracic and cervical anastomotic leakage after esophagectomy for esophageal cancer: a systematic review. World J. Emerg. Surg. 2019;14:17. https://doi.org/10.1186/s13017-019-0235-4
53. Birla R., Hoara P., Dinu D., Rosianu C., Constantinoiu S. Postoperative esophageal leaks in malignant pathology – optimal management: a systematic review. Chirurgia(Bucur). 2019;114(4):429-436. https://doi.org/10.21614/chirurgia.114.4.429
54. Newton N. J., Sharrock A., Rickard R., Mughal M. Systematic review of the use of endo-luminal topical negative pressure in oesophageal leaks and perforations. Dis. Esophagus. 2017;30(3):1-5. https://doi.org/10.1111/dote.12531
55. Virgilio E., Ceci D., Cavallini M. Surgical endoscopic vacuum-assisted closure therapy (EVAC) in treating anastomotic leakages after major resective surgery of esophageal and gastric cancer. Anticancer. Res. 2018;38(10):5581-5587. https://doi.org/10.21873/anticanres.12892
56. Rausa E., Asti E., Aiolfi A., Bianco F., Bonitta G., Bonavina L. Comparison of endoscopic vacuum therapy versus endoscopic stenting for esophageal leaks: systematic review and meta-analysis. Dis. Esophagus. 2018;31(11):1-8. https://doi.org/10.1093/dote/doy060
57. Jung D. H., Yun H. R., Lee S. J., Kim N. W., Huh C. W. Endoscopic vacuum therapy in patients with transmural defects of the upper gastrointestinal tract: a systematic review and meta-analysis. J. Clin. Med. 2021;10(11):23-46. https://doi.org/10.3390/jcm10112346
58. Tavares G., Tustumi F., Tristão L. S., Bernardo W. M. Endoscopic vacuum therapy for anastomotic leak in esophagectomy and total gastrectomy: a systematic review and meta-analysis. Dis. Esophagus. 2021;34(5):doaa132. https://doi.org/10.1093/dote/doaa132
59. Scognamiglio P., Reeh M., Karstens K., Bellon E., Kantowski M. [еt al.]. Endoscopic vacuum therapy versus stenting for postoperative esophago-enteric anastomotic leakage: systematic review and meta-analysis. Endoscopy. 2020;52(8):632642. https://doi.org/10.1055/a-1149-1741

Keywords: esophageal defect, endoscopic vacuum therapy