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of the North Caucasus
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Series ПИ #ФС 77-26521.
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ISSN 2073-8137

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Development of the adhesive process in the abdominal cavity using plastic devices in laparoscopic surgery

Sergey Minaev; Alina Nikolaevna Grigorova; Sergey Timofeev; Alexandr Obedin; Igor Gerasimenko; Oksana Vladimirova; Sofia Korablina; Anna Dmitrievna  Trivailo;

The study examined the risk of developing adhesions in the abdominal cavity using modern plastic devices used in endoscopic interventions. Two equivalent groups were formed out of 80 rats. In the first group, 40 rats were injected with a sterile fragment of classical endoscopic bag through a puncture of the anterior abdominal wall, while in the second one (40 rats) – sterile plastic was used for 3D printing in medicine. The animals were removed from the experiment on the 30th and 90th days. After the macroscopic determination of the development degree of the adhesive process, the parietal and visceral peritoneum was taken out, followed by IHC examination. As a result of the study, it was found that the plastic, which is a part of endo bags and 3D printing plastic, does not lead to the formation of viscero-parietal adhesions associated with the development of the adhesive process. Thus, using various plastic devices for 3D printing in the abdominal cavity is safe. However, additional research is needed.


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Keywords: adhesions, abdominal cavity, experiment, endoscopic device, 3D printing, laparoscopy

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy