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https://doi.org/10.14300/mnnc.2020.15131

Mast cells of bulbourethral glands in children, adolescents and youth

[Morphology]
Tatiana Boronikhin; Vasily Vladimirovich Gorsky; Alexander Nikodimovich Yatskovsky;

At autopsies of 22 children, adolescents and young men, the population of mast cells of the bulbourethral glands was studied with the determination of the relative number of cells in the glands and the calculation of indicators of their functional activity (the index of cell saturation with heparin and the index of degranulation). In infants, rather low values of the studied parameters were determined, which gradually increased during early childhood, in the first and second periods of childhood and reached maximum values in the glands of adolescents. A decrease in all parameters of mast cells was typical for young people. It is assumed that mast cells can be local regulators of glandular morphogenesis, especially active during periods of low levels of androgens in the body, realizing effects on connective tissue, glandular epithelium and myocytes of the bulbourethral glands.

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Keywords: mast cells, bulbourethral glands, morphogenesis