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Состояние костного метаболизма у детей с хроническими заболеваниями органов дыхания

[Обзоры]
Долбня Светлана Викторовна; Понамарева Виктория Романовна; Захарова Ирина Николаевна; Климов Леонид Яковлевич; Толкунова Анна Александровна; Зарытовская Наталья Владимировна; Луговский Владислав Денисович; Пентегова Дарья Алексеевна;

Обзор посвящен особенностям костного метаболизма у детей с хроническими заболеваниями органов дыхания, а именно муковисцидозом и бронхиальной астмой. Согласно результатам многочисленных исследований, пациенты с хроническими заболеваниями бронхов и лёгких подвержены преждевременному развитию дисбаланса костного ремоделирования, что клинически проявляется в форме остеопении, остеопороза и низкоэнергетических переломов. Обсуждаются факторы, оказывающие влияние на состояние костного обмена на физиологическом уровне, а также роль различных патогенетических механизмов и лекарственной терапии в снижении минеральной плотности кости у пациентов детского возраста с муковисцидозом и бронхиальной астмой.

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Ключевые слова: муковисцидоз, бронхиальная астма, остеопения, остеопороз, костный метаболизм


Учредители:
Ставропольская государственная медицинская академия
Государственный научно-исследовательский институт курортологии
Пятигорская государственная фармацевтическая академия