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Взаимосвязь гипогликемии с повышенным риском развития инсульта у больных сахарным диабетом 2-го типа старших возрастных групп

[Обзор]
Остроумова Ольга Дмитриевна; Стародубова Антонина Владимировна; Кочетков Алексей Иванович; Дё Валерия Анатольевна; Остроумова Татьяна Максимовна; Кикнадзе Тамара Давидовна;

Рассматривается проблема гипогликемических состояний у больных сахарным диабетом 2-го типа и взаимосвязь гипогликемии с риском развития инсульта. Представлены данные о влиянии различных сахароснижающих лекарственных средств на шансы формирования острого нарушения мозгового кровообращения. Описаны механизмы, опосредующие взаимосвязь гипогликемиии и инсульта с позиций активации симпатоадреналовой нервной системы, индукции коагуляционного гемостаза, агрегации тромбоцитов, стимуляции свободнорадикального окисления, возникновения эндотелиальной дисфункции.

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Ключевые слова: сахарный диабет 2-го типа, гипогликемия, инсульт, пожилой и старческий возраст


Учредители:
Ставропольская государственная медицинская академия
Государственный научно-исследовательский институт курортологии
Пятигорская государственная фармацевтическая академия