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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Metabolic and immunological effects of mineral water modified by selenium in studying of resistance mechanisms to damage into hypoxic hypoxia

[Abstracts]
Natalia Efimenko; Agnessa Kaysinova; Anna Viktorovna Abramtsova; Gayane V. Sahradyan;

Simulation in rats of interval normobaric hypoxic hypoxia with hypercapnia (INHHwithH) with a duration of 17 days resulted in a decrease in the cellularity of the thymus and spleen, glycemia and an increase in neutrophilic granulocytes in the peripheral blood and a decrease in their oxygen-dependent biocidal activity. The preventive course of the mineral water of the Krasnoarmeysky New spring mineral water (MW) with selenium added as a dimethyldipyrazoleselenide substance based on the selenium content of 250 μg/kg prior to INHHwithH modeling reduced manifestations of the damaging effect of hypoxia.

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References:

1.Fizicheskaya i reabilitacionnaya medicina. Nacionalnoe rukovodstvo / ed. by. G. N. Ponomarenko. M.: «GEOTAR-Media»; 2016. (In Russ.).
2. Senkevich O. A., Golubkina N. A., Kovalsky Yu. G. Diagnostika obespechennosti cheloveka selenom i otsenka stepeni yego defitsita. Dal’nevostochnyy meditsinskiy zhurnal. – Far Eastern Medical Journal. 2011;(4):78-80. (In Russ.).
3. Rayman M. P. Selenium and human health. The Lancet. 2012;379(9822):1256-1268. https://doi.org/10.1016/S0140-6736(11)61452-9
4. Selim N. A., Radwan N. L., Youssef S. F. Effect of Inclusion Inorganic, Organic or Nano Selenium Forms in Broiler Diets On: 2-Physiological, Immunological and Toxicity Statuses of Broiler Chicks. International Journal of Poultry Science. 2015;14:144-155.
5. Pekhovskaya T. A., Tarasov Yu. A., Katkovskaya I. N., Elchaninova M. A., Alftan G. V. [et al.]. Selenomethionine and dimethyl dipyrazolyl selenide (selecor) as protectors of oxidative stress. Zdorov’e i okruzhayushaya sreda. – Health and environment. 2009;13:408-413. (In Russ.).

Keywords: mineral water, selenium, hypoxic hypoxia


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