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of the North Caucasus
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ISSN 2073-8137

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Metabolic and immunological effects of mineral water modified by selenium in studying of resistance mechanisms to damage into hypoxic hypoxia

Natalia Efimenko; Agnessa Kaysinova; Anna Viktorovna Abramtsova; Gayane V. Sahradyan;

Simulation in rats of interval normobaric hypoxic hypoxia with hypercapnia (INHHwithH) with a duration of 17 days resulted in a decrease in the cellularity of the thymus and spleen, glycemia and an increase in neutrophilic granulocytes in the peripheral blood and a decrease in their oxygen-dependent biocidal activity. The preventive course of the mineral water of the Krasnoarmeysky New spring mineral water (MW) with selenium added as a dimethyldipyrazoleselenide substance based on the selenium content of 250 μg/kg prior to INHHwithH modeling reduced manifestations of the damaging effect of hypoxia.



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Keywords: mineral water, selenium, hypoxic hypoxia

Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy