• Main page
• About the journal
• Editorial board
• Subscription
• Information for contributors
• Editorial and Peer Review
• Issues archive
• Authors
• Articles
  • By alphabet
  • By category
• Blogs and comments

The journal is included into The list of leading scientific periodicals.

The journal is included into VINITI database and is registered in Electronic scientific library.

The journal is indexed by SCOPUS, Ulrich's International Periodicals Directory.

EBSCO

Histochemical characteristics of the condition of the nervous apparatus of the masseter and the parotid gland in the systematic exposure of general vibration and pharmacological correction in the experiment

[Original research] [Experimental medicine]
Ivan Vasilyevich Gaivoronsky; Andrey Iordanishvili; Aleksandr Kovalevsky; Pavel Stepanovich Pashchenko; Maria Georgievna Gaivoronskaya;

In order to study the state of the organs and tissues of the chewing apparatus when the body is exposed to general vibration and the possibilities of pharmacological correction of morphological and functional changes in the experiment on white rats, a systematic effect of vertical general vibration with a vibration frequency of 50 Hz, a vibration acceleration of 0.35 m/s or 63.5 DB, vibration velocity – 0.12 m/s or 100 dB, with an amplitude of 2 mm, in addition, simulated the vibration effect against the background of intraperitoneal injections of antihypoxant amtizol (25 mg/kg) and the adaptogen ethylthiobenzimidazole (12.5 mg/kg), and their combinations. Investigated the morphofunctional state of nerve fibers by determining the optical density of the products of cytochemical reactions to identify noradrenaline, acetylcholinesterase and butyrylcholinesterase in them. The intensity of luminescence of norepinephrine in the nerve fibers after exposure to vibration compared with the control increased, which may indicate the generalization of excitation in the sympathetic division of the autonomic nervous system; the optical density of the product of the histochemical reaction of both enzymes is reduced in the nerve trunks of the parotid gland, and BTH – in the nerve fibers of the perivasal plexus of arterioles, which indicates the inhibition of their activity. Pharmacologic prophylaxis with the help of an antihypoxant and an adaptogen reduces the negative impact of vibration on the body of an experimental animal.

Download

References:
1. Nesina I. A., Efremov A. V., Shpagina L. A., Poterjaeva E. L., Rehtin N. F. [et al.]. State of hormonal regulation in the dynamics of rehabilitation treatment in patients with vibration disease. Zhurnal eksperimentalnoj i klinicheskoj mediciny. – Journal of Experimental and Clinical Medicine. 2003;(2-3):42-46. (In Russ.).
2. Shpagina L. A., Zakharenkov V. V. Comparative analysis of the clinical manifestations of vibration disease of varying severity. Medicina truda i promyshlennaja jekologija. – Occupational medicine and industrial ecology. 2006;(6):20-23. (In Russ.).
3. Bovenzi M. Metrics of whole-body vibration and exposureresponse relationship for low back pain in professional drivers: a prospective cohort study. International Journal of Occupational and Environmental Health. 2009;82(7):893-917. https://doi.org/10.1007/s00420-008-0376-3
4. Chao P. C., Juang Y. J., Chen C. J., Dai Y. T., Yeh C. Y.[et al.]. Combined effects of noise, vibration and low temperature on the physiological parameters of labor employeers. The Kaohsiung Journal of Medical Sciences. 2013;29(10):560-567. https://doi.org/10.1016/j.kjms.2013.03.004
5. Bondarev E. V., Egоrov V. A., Novikov V. S., Lustin S. I. Medical support for ground and deck helicopter flights: a tutorial. St. Petersburg: VMedA; 1995. (In Russ.)].
6. Pozharitskaya M. M., Isakov T. G., Biryukov R. Yu., Vavilova T. P., Krasnova V. V. Changes in the enzymatic activity of mixed saliva during periodontitis in supersonic pilots. Parodontologija. – Periodontology. 2004;(4):3-7. (In Russ.)].
7. Sasaki Y., Takahashi Y., Arita K., Kawanishi S., Ishii T. Assessment of periodontal treatment needs in Japan maritine self-defense force by CPITN. The Bulletin of Tokyo Dental College. 1988;29(1):21-25.
8. Curry B. D., Bain J. L., Yan J. G., Zhang L. L., Yamaguchi M. [et al.]. Vibration injury damages arterial endothelial cells. Muscle & Nerve. 2002;25(4):527-534.
9. Gajvoronskij I. V., Balin V. N., Iordanishvili A. K., Tihonova L. P., Kovalevskij A. M. Experimental morphological data on the effect of gravitational overload on the state of the organs and tissues of the masticatory apparatus. Novoe v stomatologii. – New in dentistry. 1996;(1):41-42. (In Russ.).
10. Falck B., Hillarp N. A., Torp A., Thieme G. Fluorescence of cateholamines and related compounds condensed with formaldehyde. Journal of Histochemistry & Cytochemistry. 1962;10(2):348-354.
11. Karnovsky M. C., Rootz Z. A. Direct-coloring thiocholine method for cholinesterase. Journal of Histochemistry & Cytochemistry. 1964;12:219-221.
12. Gayvoronsky I. V., Prohvatilov G. I.,. Iordanishvili A. K., Gayvoronskaya V. V., Tikhonova L. P. [et al.]. Local immunity of the oral cavity during gravitational overloads. Klinicheskaja patofiziologija. – Clicical Phathophysiology. 2003;(2):36-40. (In Russ.)

Keywords: general vibration, masseter, parotid gland, norepinephrine, antihypoxants, adaptogens