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https://doi.org/10.14300/mnnc.2019.14050

The effect of type 2 diabetes mellitus on the course of chronic obstructive pulmonary disease

[Internal diseases]
Andrei Budnevskiy; Natalia Polyakova; Evgeniy Ovsyannikov; Zarema Alimkhanova;

This article reviews the results of a comparative analysis of 80 cases of patients with chronic obstructive pulmonary disease (COPD). Of these, 40 cases of patients with comorbid pathology (COPD and type 2 diabetes mellitus) and 40 cases of COPD patients without type 2 diabetes. The data of questionnaires, tests, clinical and laboratory and instrumental indicators were analyzed. There was demonstrated negative role of type 2 diabetes on the course of COPD by such indicators as the frequency of exacerbation of COPD per year, the frequency of calls of ambulance team, the frequency of hospitalizations for exacerbation or deterioration of the course of COPD, clinical symptoms of COPD, spirometry parameters and cytokine and adipocytokine profiles.

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Keywords: chronic obstructive pulmonary disease, type 2 diabetes mellitus, cytokine, adipocytokine, quality of life