logo
Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
rus
русский
eng
english

Site search



Correspondence address
310 Mira Street, Stavropol, Russia, 355017

Tel
+7 865 2352511, +7 865 2353229.

E-mail
medvestnik@stgmu.ru

Irritable bowel syndrome: pathophysiological role of intestinal dysbiosis and possibilities of its modulation

[Reviews]
Kubanich Aitbaev; Ilhom Murkamilov; Viktor Fomin; Furkat Yusupov; Nodira Redjapova; Zafarbek Raimzhanov; Ziyabidin Aidarov;

The review presents data on the relationship of intestinal dysbiosis with irritable bowel syndrome (IBS) and the possibility of modulation of the intestinal microbiota (MB) in IBS therapy. It is shown that imbalance of MB caused by the influence of diet, antibiotics or other exogenous factors leads to gastrointestinal disorders, in particular, to the development of IBS. The data are presented that the modulation of MB with the help of prebiotics, antibiotics, probiotics and fecal microbiota transplantation has a positive therapeutic effect in patients with IBS.

Download

References:
1. Bondareva N. I., Timchenko L. D., Alieva E. V., Dobrynja Yu. M., Gandraburova N. I., Piskov S. I., Kalmykova L. Medicinskii vestnik Severnogo Kavkaza. – Medical news of North Caucasus. 2017;12(1):87-90. doi: 10.14300/ mnnc.2017.12024
2. Andrews P., Borody T., Shortis N. P., Thompson S. Gastroenterology. 1995;108:A563.
3. Backhed F., Ding H., Wang T. Proc. Natl. Acad. Sci. USA. 2004;101:15718-15723. doi: 10.1073/pnas.0407076101
4. Bovee-Oudenhoven I. M., Bruggencate S. J., Lettink- Wissink M. I. Gut. 2003;52:1572-1578. doi: 10.1136/ gut.52.11.1572
5. Brandt L. J. Am. J. Gastroenterol. 2013;108(2):177-185. doi: 10.1038/ajg.2012.450
6. Brenner D. M., Moeller M. J., Chey W. D. Am. J. Gastroenterol. 2009;104(4):1033-1049. doi: 10.1038/ajg.2009.25
7. Carroll I. M., Ringel-Kurka T., Siddle J. P., Ringel Y. Neurogastroenterol. Motil. 2012;24(6):521-530. doi: 10.1111/j.1365-2982.2012.01891.x
8. Chassard C., Dapoignu M., Scott K. P. Aliment. Pharmacol. Ther. 2012;35(7):828-838. doi: 10.1111/j.1365- 2036.2012.05007.x
9. Codling C., O’Mahony L., Shanahan F. Dig. Dis. Sci. 2010;55(2):392-397. doi:10.1007/s10620-009-0934-x
10. De Roest R. H., Dobbs B. R., Chapman B. A. Int. J. Clin Pract. 2013;67:895-903. doi: 10.1111/ijcp.12128
11. Dupont H. L. Aliment. Pharmacol. Ther. 2014;39(10):1033- 1042. doi:10.1111/apt.12728
12. Durban A., Abellan J., Jimenez-Hernandez N. Environ. Microbiol. Rep. 2012;4(2):242-247. doi: 10.1111/j.1758- 2229.2012.00327.x
13. Eswaran S., Tack J., Chey W. D. Gastroenterol. Clin. North. Am. 2011;40:141-162. doi: 10.1016/j.gtc.2010.12.012
14. Ford A. C., Quigley E. M., Lacy B. E. Am. J. Gastroenterol. 2014;109:1547-1561. doi: 10.1038/ajg.2014.202
15. Frank D. N., Amand St. A. L., Feldman R. A. Proc. Natl. Acad. Sci. USA. 2007;104(34):13780-13785. doi: 10.1073/pnas.0706625104
16. Gralnek I. M., Hays R. D., Kilbourne A. Gastroenterology. 2000;119(3):654-660. doi: 10.1053/gast.2000.16484
17. Grehan M. J., Borody T. J., Leis S. M. J. Clin. Gastroenterol. 2010;44(8):551-561. doi: 10.1097/MCG.0b013e3181e- 5d06b
18. Halmos E., Power V., Shepherd S. Gastroenterology. 2014;146:67-75. doi: 10.1053/j.gastro.2013.09.046
19. Halvorson H. A., Schlett C. D., Riddle M. S. Am. J. Gastroenterol. 2006; 101(8):1894-1899. doi: 10.1111/j.1572- 0241.2006.00654.x
20. Hungin A. P., Mulligan C., Pot B. Aliment. Pharmacol. Ther. 2013;38:864-886. doi: 10.1111/apt.12460
21. Jalanka-Tuovinen J., Salojarvi J., Salonen A. Gut. 2014;63(11):1737-1745. doi: 10.1136/gutjnl- 2013-305994
22. Jeffery I. B., O’Toole P. W., Ohman L. Gut. 2012;61:997- 1006. doi: 10.1136/gutjnl-2011-301501
23. Kassinen A., Krogius Kurikka L., Makivuokko H. Gastroenterology. 2007;133(1):24-33. doi: 10.1053/j.gastro. 2007.04.005
24. Krogius-Kurikka L., Lyra A., Malinen E. BMC Gastroenterol. 2009;9:95. doi: 10.1186/1471-230X-9-95
25. Maxwell P. R., Rink E., Kumar D., Mendall M. A. Am. J. Gastroenterol. 2002;97(1):104-108. doi: 10.1111/j.1572- 0241.2002.05428.x
26. Menees S. B., Maneerattanaporn M., Chey W. D. Gastroenterology. 2011;140:49-50.
27. Moayyedi P., Ford A. C., Talley N. J. Gut. 2010;59:325- 332. doi: 10.1136/gut.2008.167270
28. Ng S. C., Lam E. F., Lam T. T. J. Gastoenterol. Hepatol. 2013;28(10):1624-1631. doi: 10.1111/jgh.12306
29. O’Hara A. M., Shanahan F. EMBO Rep. 2006;7:688-693. doi: 10.1038/sj.embor.7400731
30. Ong D. K., Mitchell S. B., Barrett J. S. J. Gastroenterol. Hepatol. 2010;25:1366-1373. doi: 10.1111/j. 1440-1746.2010.06370.x
31. Parkes G. C., Rayment N. B., Hudspith B. N. Neurogastroenterol. Motil. 2012;24(1):31-39. doi: 10.1111/j.1365- 2982.2011.01803.x
32. Penders J., Thijs C., Vink C. Pediatrics. 2006;118:511- 521. doi:10.1542/peds.2005-2824
33. Pimentel M., Chow E. J., Lin H. C. Am. J. Gastroenterol. 2003;98:412-419. doi: 10.1111/j.1572- 0241.2003.07234.x
34. Pimentel M., Lembo A., Chey W. D. N. Engl. J. Med. 2011;364:22-32. doi:10.1056/NEJMoa1004409
35. Posserud I., Stotzer P.-O., Bjornsson E. Gut. 2007;56:802- 808. doi: 10.1136/gut.2006.108712
36. Quigley E. M. J. Dig. Dis. 2007;8:2-7.
37. Rajilic-Stojanovic M., Biagi E., Heilig H. G. Gastroenterology. 2011;141:1792-1801. doi: 10.1053/j. gastro.2011.07.043
38. Rohlke F., Surawicz C. M., Stollman N. J. Clin. Gastroenterol. 2010;44:8.-567-570. doi: 10.1097/MCG.0b013e- 3181dadb10
39. Shepherd S. J., Parker F. C., Muir J. G. Clin. Gastroenterol. Hepatol. 2008;6:765-771. doi: 10.1016/j. cgh.2008.02.058
40. Shepherd S. J., Gibson P. R. J. Am. Diet. Assoc. 2006;106:1631-1639. doi: 10.1016/j.jada.2006.07.010
41. Simren M., Barbara G., Flint H. J. Gut. 2013;62(1):159- 176. doi: 10.1136/gutjnl-2012-302167
42. Smits L. P., Bouter K. E., de Vos W. M. Gastroenterology. 2013;145(5):946-953. doi: 10.1053/j.gastro.2013.08.058
43. Staudacher H. M., Lomer M. C., Anderson J. L. J. Nutr. 2012;142:1510-1518. doi: 10.3945/jn.112.159285
44. Steer T., Carpenter H., Tuohy K. Nutr. Res. Rev. 2000;13: 229-254. doi: 10.1079/095442200108729089
45. Thabane M., Kottachchi D. T., Marshall J. K. Aliment. Pharmacol. Ther. 2007;26(4):535-544. doi: 10.1111/j.1365- 2036.2007.03399.x
46. Tornblom H., Holmvall P., Svenungsson B., Lindberg G. Clin. Gastroenterol. Hepatol. 2007;5(4):461-464. doi: 10.1016/j.cgh.2007.01.007
47. Whitman W. B., Coleman D. C., Wiebe W. J. Proc. Natl. Acad. Sci. USA. 1998;95(12):6578-6583. PMCID: PMC33863
48. Xu J., Gordon J. I. Proc. Natl. Acad. Sci. USA. 2003;100(18):10452-10459. doi: 10.1073/pnas. 1734063100

Keywords: irritable bowel syndrome, gut microbiota, prebiotics, probiotics, antibiotics, fecal microbiota transplantation


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy