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Medical news
of the North Caucasus
Scientific journal
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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Experimental estimation of the structure of endothely of parodont vesselsin the dynamics of the inflammatory process

[Morphology]
Alla Sirak; Evgeny Shchetinin; Natalia Bykova; Gregory Petrosyan; Sergey Sirak; Roman Romanenko;

The results of the evaluation of the endothelium structure of the periodontal vessels of the upper and lower jaw of rats in norm and in the modeling of periodontitis were presented. From the first day, changes in the cytostructure of cells affect the length, thickness of endotheliocytes and pericytes, the number of mitochondria, the Golgi complex, the reticulum of the endothelium, and the amount of heterochromatin in the nucleus. Complex structural changes trigger the reactions of the microcirculatory bed of periodontal tissues with a violation of the rheological properties of the blood, the formation of exudate and an inflammatory cellular infiltrate. Beginning from the 14th day, proliferative changes appear more pronounced in the vessels of the upper jaw, which ensure, by the 30th day of parodontitis modeling, the preservation of the regulation of the tone of blood vessels, the emigration of blood cells and the activation of local proliferation processes.

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References:
1. Arushanyan E. B., Shchetinin E.V. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2015;10(2):196-206. doi: 10.14300/mnnc.2015.10046
2. Gaynullina D. K., Kiryukhina O. O., Tarasova O. S. Uspechi fiziologicheskich nauk. – Advances of Physiological Science. 2013;44(4):88-102.
3. Gurevich K. G., Dmitrieva L. A., Tebloeva L. M., Pochtarenko V. A., Erochin A. I. Periodontit. XXI. M.: 2016.
4. Degtjar N. I., Gerasimenko N. D., Rasin M. S. Arterialnaya gipertenziya. – Hypertension. 2016;4:21-25. doi: 10.22141/2224-1485.4.48.2016.76991
5. Sirak S. V., Kobylkina T. L., Sirak A. G., Vafiadi M. Yu., Bykova N. I. Parodontologiya. – Periodontology. 2017;22(2):27-30.
6. Shchetinin E. V., Sirak S. V., Grigoryants L. A., Vafiadi M. Yu., Dilekova O. V. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2015;10(4):411-415. doi: 10.14300/mnnc.2015.10100
7. Yakovlev V. M., Yagoda A. V. Metabolicheskii sindrom i sosudistii endotelii. Stavropol, 2008.
8. Celermajer D. S. Journal of the American College of Cardiology, 1997;30(2):325-333. doi: 10.1016/S0735- 1097(97)00189-7
9. Félétou M., Huang Y., Vanhoutte P. M. British Journal of Pharmacology. 2011;164(3):894-912. doi: 10.1111/j. 1476-5381.2011.01276.x
10. Liu X., Wang J., Dong F., Li H., Hou Y. Development Growth and Differentiation. 2016;58(9):702-713. doi: 10.1111/dgd.12327
11. Sata M., Maejima Y., Adachi F., Fukino K., Saiura A. Journal of Molecular and Cellular Cardiology. 2000;32(11):2097- 2104. doi: 10.1006/jmcc.2000.1238

Keywords: endothelium, periodontium


Founders:
Stavropol State Medical Academy
Pyatigorsk State Research Institute of Balneotherapeutics
Pyatigorsk State Pharmaceutical Academy