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Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Is there a relationship between insulin resistance, erectile dysfunction and the level of serum total testosterone in men with type 2 diabetes mellitus

[Abstracts]
Irina Khripun; Igor Belousov; Sergey Vorobyev; Valentina Puzyreva; Yanina Allakhverdieva; Halid Ibishov; Michail Kogan;

The aim of the study was to evaluate the influence of serum total testosterone (T) on the insulin resistance (IR) and erectile dysfunction in men with type 2 diabetes mellitus (T2DM). Objects were 131 male aged 40-65 years with T2DM. Symptoms of erectile dysfunction and androgen deficiency were assessed by IIEF-5 and AMS questionnaires, IR – by HOMA index. Patients were divided into four groups depending on the level of total T. Weight, body mass index and waist circumference were significantly increased in patients with a decreased level of T. The severity of IR negatively correlated with the T levels. Severity of the symptoms of androgen deficiency and erectile dysfunction increases with the decrease in T levels accompanied by worsening of IR in men with T2DM. Supported by Russian Science Foundation, grant № 14-25-00052

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References:
1. Gusova Z., Khripun I., Dzantieva E., Vorobiev S., Elenga- Bongo C. L. Diabet. Metabol. 2015;41(1):A45.
2. Kelly D. M., Jones T. H. J. Endocrinol. 2013;217:25-45.
3. Khripun I. A., Dzantieva E. O., Vorobyev S. V., Belousov I. I., Ibishev H. S., Gusova Z. R., Haritonova M. I., Sultanmuradova A. S., Kogan M. I., Zitzmann M. Influence of endogenous testosterone on markers of endothelial dysfunction in men with type 2 diabetes. Prague: Abstract book ISSAM. 2015. Р. 11.
4. Saghier E. O., Shebl S. E., Fawzy O. A. Clin. Med. Insights Endocrinol. Diabetes. 2015;19(8):55-62.
5. Traish A. M., Saad F., Guay A. J. Androl. 2009;30(1):23- 32.

Keywords: testosterone, diabetes mellitus, insulin resistance, erectile


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