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[Original research] [Experimental medicine]
Sergey Sirak; Evgeny Shchetinin; Tatyana Kobylkina; Olga Dilekova; Alla Sirak; Liana Parazyan; Marina Vafiadi;
The role of C-kit-positive cells of the tooth pulp in optimization of reparative dentinogenesis in biological methods of treatment of pulpitis in exremental animals was studied. A model of acute pulpitis with subsequent amputation of the vital pulp was received in vivo on 80 incisors of the lower jaw of he-sheep. The use of tissue-engineered construction composed of collagen sponge, hydrogel PuraMatrix/3DM and ectomesenchymal cells as a biological methods of treatment has allowed to protect better the pulp against infection, to optimize the inflammatory process with the activation of proliferation and acceleration of formation of dentinal bridge.
References:
1. Sirak A. G., Sirak S. V. Sovremennie problem nauki i obrazovaniya. – Modern problems of science and education. 2013;2:44.
2. Sirak A. G., Sirak S. V. Fundomentalnie issledovaniya. – Fundomental research. 2013;5-2:384-388.
3. Sirak A. G., Parazyan L. A., Shchetinin E. V., Sirak S. V., Vafiadi M. Yu. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2015;10(4):384-388.
4. Sirak S. V., Sirak A. G., Kopylova I. A., Biragova A. K. Medicinskii vestnik Severnogo Kavkaza. – Medical News of North Caucasus. 2011;23(3):29-33.
5. Ashman L. K. International Journal of Biochemistry and Cell Biology. 1999;31(10):1037-1051. doi: 10.1016/ S1357-2725(99)00076-X
6. Avila-Ortiz G., Buitrago J. G. D., Reddy M. S. Journal of Periodontology. 2015;86: S108-S130. DOI: 10.1902/ jop.2015.130677
7. Claus I., Laureys W., Cornelissen R., Dermaut L. R. American Journal of Orthodontics and Dentofacial Orthopedics. 2004;125(1):93-99. doi: 10.1016/S0889- 5406(03)00619-X
8. Ding R., Jiang X., Ha Y., Wang Z., Guo J., Jiang H. Stem Cell Research and Therapy. 2015; http://stemcellres. com doi: 10.1186/s13287-015-0085-2
9. Grimm W. D., Dannan A., Giesenhagen B., Schau I., Varga G., Vukovic M. A. International Journal of Stem Cells. 2014;7(1):23-29.
10. Grimm Dr. W.-D., Ploger M., Schau I., Vukovic M. A., Shchetinin E. V., Akkalaev А. B. Medical news of North Сaucasus. 2014;9(2):131-133. doi: 10.14300/ mnnc.2014.09037
11. Han C., Yang Z., Zhou W., Jin F., Song Y., Wang Y. Stem Cells and Development, 2010;19(9):1405-1415. doi: 10.1089/scd.2009.0277
12. Kanafi M. M., Ramesh A., Gupta P. K., Bhonde R. R. International Endodontic Journal. 2014;7(7):687-697. doi: 10.1111/iej.12205
13. Kim B.-C. Bae H., Kwon I.-K., Lee E.-J., Park J.-H., Khademhosseini A. Tissue Engineering – Part B: Reviews. 2012;18(3):235-244. doi: 10.1089/ten. teb.2011.0642
14. Lee Y.-H., Kang Y.-M., Heo M.-J., Kim G.-E., Bhattarai G., Lee N.-H. Journal of Endodontics, 2013;39(2):236- 241. doi: 10.1016/j.joen.2012.11.006
15. Lin Z., Rios H.F., Cochran D. L. Journal of Periodontology. 2015;86:S134-S152. DOI: 10.1902/jop.2015.130689
16. Murakami S. Periodontology 2000. 2011;56(1):188- 208. doi: 10.1111/j.1600-0757.2010.00365.x
17. Shchetinin E. V., Sirak S. V., Khodzhayan A. B., Dilekova O. V., Sirak A. G., Vafiadi M. Y. Medical News of North Caucasus. 2015;10(2):187-191. doi: 10.14300/ mnnc.2015.10044
Keywords: pulpitis, tissue-engineered construction, ectomesenchymal cells