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[Abstracts]
Natalya Bulgakova; Madina Baikulova; Elena Scheglova; Vladimir Kolesnikov; Alexandr Yagoda; Olga Boeva;
In a prospective cohort study the effect of the fibrinogen β-chain gene polymorphism -455G-A and fibrinogen plasma levels on the risk of stroke and systemic thromboembolism in 102 patients (83.3 % men, mean age 52.9±8.4 yrs) with non-valvular atrial fibrillation. Identification of fibrinogen B gene 455G-A polymorphism can be useful to customize the anticoagulation strategy in patients with atrial fibrillation.
References:
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Keywords: atrial fibrillation, fibrinogen, thromboembolic complications, genetic polymorphism, fibrinogen β-chain gene