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Medical news
of the North Caucasus
Scientific journal
Mass media registration certificate dated December 7, 2006.
Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Effect of melatonin on the level of thyrotropic hormones in experimental hypothyroi dism in rats

[Abstracts]
Karine Elbekyan; Evgenia Markarova; Anna Khodzhayan; Margarita Gevandova;

A laboratory rat´s model was used to study the changes in the hormonal activity in the pituitary-thyroid system under the impact of melatonin given in physiological doses. It has been shown that melatonin has a stimulating effect against the background of reduced thyroid activity.

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References:
1. Arushanyan E. B., Beyer E. V. Melatonin: biology, pharmacology, clinic. 2015: 395 p.
2. Claustrat B., Leston J. Melatonin: Physiological effects in humans. Neurochirurgie. 2015;61(2):77-84.
3. Esquifino A., Agrasal C., Velázquez E. Effect of melatonin on serum cholesterol and phospholipid levels, and on prolactin, thyroid-stimulating hormone and thyroid hormone levels, in hyperprolactinemic rats. Life Sci. 1997;61(11):1051-1058.
4. Garcia-Marin R., Fernandez-Santos J. M., Moril-lo-Bernal J. Melatonin in the thyroid gland: regulation by thyroid-stimulating hormone and role in thyroglobulin gene expression. J. Physiol Pharmacol. 2015;66(5):643-652.
5. Vriend J., Sheppard M. S., Bala R. M. Effects of melatonin and hypothyroidism on somatomedin levels of female Syrian hamsters. J Pineal Res. 1989;7(1):85-90.

Keywords: experimental model of hypothyroidism, melatonin, thyrotropic hormones, rats


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