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Series ПИ #ФС 77-26521.
Federal service for surveillance over non-violation of the legislation in the sphere of mass communications and protection of cultural heritage.
ISSN 2073-8137
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Influence of pinealectomy on some hemathologic indices and activity of antireumathoid drugs in rats with aduvant arthritis

[Pharmacology]
Stanislav Naumov; Ksenia Lomonosova; Eduard Arushanyan;

In the experimental model of rheumatoid arthritis it was determined that in the blood of rats with remote epiphysis, compared to falsely operated animals, plasma melatonin content falls, the level of cortisol increases and indicators of inflammation increase. At the same time, inflammatory activity of prednisolone and diclofenac changes. The outside introduction of the drug of melatonin is accompanied by a limitation of humoral parameters of inflammation.

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Keywords: arthritis, pinealectomy, melatonin, anti-inflammatory drugs


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